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PLAUR Protein (AA 23-303) (His tag)

PLAUR Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Catalog No. ABIN2181889
  • Target See all PLAUR Proteins
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-303
    Origin
    • 27
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 23
    • 13
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PLAUR protein is labelled with His tag.
    Sequence
    AA 23-303
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.1 kDa. The protein migrates as 44-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >92 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product PLAUR Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    Alternative Name
    uPAR (PLAUR Products)
    Synonyms
    Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein
    Background
    Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
    Molecular Weight
    32.3 kDa
    Pathways
    Inositol Metabolic Process
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