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Dermcidin antibody

DCD Reactivity: Human WB, IHC (p), IA Host: Mouse Monoclonal G-81 unconjugated
Catalog No. ABIN2191909
  • Target See all Dermcidin (DCD) Antibodies
    Dermcidin (DCD)
    Reactivity
    • 37
    • 2
    Human
    Host
    • 35
    • 2
    Mouse
    Clonality
    • 35
    • 2
    Monoclonal
    Conjugate
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dermcidin antibody is un-conjugated
    Application
    • 31
    • 17
    • 13
    • 13
    • 10
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoassay (IA)
    Endotoxin Level
    Low endotoxin level
    Clone
    G-81
    Top Product
    Discover our top product DCD Primary Antibody
  • Application Notes
    For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Restrictions
    For Research Use only
  • Buffer
    1 mL(> 200 μg/mL) culture medium with a low endotoxin level containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Minami, Uede, Sagawa, Kimura, Tsuji, Furukawa: "Immunohistochemical staining of cutaneous tumours with G-81, a monoclonal antibody to dermcidin." in: The British journal of dermatology, Vol. 151, Issue 1, pp. 165-9, (2004) (PubMed).

    Sagawa, Kimura, Saito, Inoue, Yasuda, Nosaka, Tsuji: "Production and characterization of a monoclonal antibody for sweat-specific protein and its application for sweat identification." in: International journal of legal medicine, Vol. 117, Issue 2, pp. 90-5, (2003) (PubMed).

  • Target
    Dermcidin (DCD)
    Alternative Name
    Dermcidin (DCD Products)
    Synonyms
    AIDD antibody, DCD-1 antibody, DSEP antibody, HCAP antibody, PIF antibody, dermcidin antibody, DCD antibody
    Background
    The monoclonal antibody G-81 recognizes a fragment of human dermcidin (DCD). The antibiotic peptide dermcidin (110 amino acids) is specifically and constitutively expressed in the sweat glands. DCD is localized to the dark mucous cells of normal eccrine sweat glands. DCD is normally expressed in eccrine sweat glands and is expressed in cutaneous mixed tumours. DCD-immunopositive cells are expressed in the inner cells of the tubular and ductal structures. The monoclonal antibody G-81 was produced against a sweat-specific antigen. It reacts to sweat but not to other body fluids (e.g. serum, saliva, semen, milk, urine and tears) in ELISA. The N-terminal amino acid sequence (18 amino acids residues) is identical to a part of human cachexia-associated protein and of a survival-promoting peptide for neuronal cells. Besides this, the sequence is identical to the C-terminal peptide (amino acids 62-79) of DCD. The monoclonal antibody G81 can be used as a specific marker for eccrine glands in the human skin. The monoclonal antibody G-81 is useful as a immunohistochemical tool to find the tumour cells that differentiate towards eccrine secretory cells in cutaneous mixed tumours. Furthermore, the antibody can be used for the detection of biochemical and histochemical changes of the sweat gland in the healing process of wound. Aliases AIDD, PIF, DSEP, HCAP, DCD-1 Immunogen Fractioned sweat peptides in complete Freund's adjuvant
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