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C5 antibody

C5 Reactivity: Human WB, IA Host: Mouse Monoclonal 568 unconjugated
Catalog No. ABIN2191951
  • Target See all C5 Antibodies
    C5 (Complement Component 5 (C5))
    Reactivity
    • 123
    • 32
    • 19
    • 16
    • 2
    • 2
    • 2
    Human
    Host
    • 113
    • 14
    • 6
    • 4
    Mouse
    Clonality
    • 123
    • 13
    Monoclonal
    Conjugate
    • 48
    • 13
    • 12
    • 9
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    This C5 antibody is un-conjugated
    Application
    • 68
    • 50
    • 42
    • 39
    • 26
    • 20
    • 12
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoassay (IA)
    Sterility
    0.2 μm filtered
    Clone
    568
    Top Product
    Discover our top product C5 Primary Antibody
  • Application Notes
    It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Mollnes, Klos, Tschopp: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." in: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).

  • Target
    C5 (Complement Component 5 (C5))
    Alternative Name
    c5/c5b (C5 Products)
    Synonyms
    C5 antibody, LOC565774 antibody, C5a antibody, C5b antibody, CPAMD4 antibody, Hc antibody, RGD1561905 antibody, He antibody, complement C5 antibody, complement component 5 antibody, hemolytic complement antibody, C5 antibody, c5 antibody, Hc antibody
    Background
    Monoclonal antibody 568 reacts with an epitope on C5 and on C5b. C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.
    Pathways
    Complement System, Carbohydrate Homeostasis
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