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C3 antibody

C3 Reactivity: Rat WB, IA Host: Mouse Monoclonal 2B10B9B2 unconjugated
Catalog No. ABIN2192120
  • Target See all C3 Antibodies
    C3 (Complement Component 3 (C3))
    Reactivity
    • 94
    • 57
    • 34
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    Rat
    Host
    • 72
    • 47
    • 27
    • 8
    • 7
    • 6
    Mouse
    Clonality
    • 129
    • 37
    Monoclonal
    Conjugate
    • 74
    • 24
    • 24
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This C3 antibody is un-conjugated
    Application
    • 109
    • 54
    • 40
    • 35
    • 34
    • 30
    • 30
    • 29
    • 23
    • 18
    • 14
    • 13
    • 13
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoassay (IA)
    Endotoxin Level
    Low endotoxin level
    Clone
    2B10B9B2
    Top Product
    Discover our top product C3 Primary Antibody
  • Application Notes
    For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Restrictions
    For Research Use only
  • Buffer
    1 mL(> 100 μg/mL) culture medium with a low endotoxin level containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Target
    C3 (Complement Component 3 (C3))
    Alternative Name
    c3/c3b (C3 Products)
    Synonyms
    AHUS5 antibody, ARMD9 antibody, ASP antibody, C3a antibody, C3b antibody, CPAMD1 antibody, AI255234 antibody, HSE-MSF antibody, Plp antibody, C3 antibody, C3-1 antibody, sb:cb26 antibody, si:dkey-76b14.4 antibody, wu:fi34b03 antibody, wu:fj86e11 antibody, C3d antibody, asp antibody, cpamd1 antibody, c3 antibody, complement C3 antibody, complement component 3 antibody, complement component c3a, duplicate 1 antibody, complement component 3 L homeolog antibody, complement component C3 antibody, complement C3-like antibody, C3 antibody, c3a.1 antibody, c3.L antibody, LOC443475 antibody, c3 antibody, c3-1 antibody, LOC100060539 antibody
    Background
    The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b. The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha- chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
    Pathways
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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