anti-Cytochrome C antibody (Cytochrome C, Somatic)

Details for Product anti-CYCS Antibody No. ABIN222880, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

cyct, cyc, hcs, CYCS, cycs, CYC, CG13263, Cyt C, Cyt c, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, Dmel\\CG13263, bln, bs30f07.y1, cyt c, cyt c-d, cyt-c-d, cyt.c, cytochrome c, dc3, ms(2)04445, pDMc02, ... show more
cyct, cyc, hcs, CYCS, cycs, CYC, CG13263, Cyt C, Cyt c, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, Dmel\\CG13263, bln, bs30f07.y1, cyt c, cyt c-d, cyt-c-d, cyt.c, cytochrome c, dc3, ms(2)04445, pDMc02, CG17903, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, Dmel\\CG17903, cyt c-p, cyt-c-p, cyt-c2, dc4, pDMc01, HCS, THC4, cytc, CYCSA, wu:fk52b01, zgc:86706, ENSMUSG00000058927 show less
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(175), (91), (88), (45), (18), (16), (10), (8), (8), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
(142), (107), (7), (4)
This Cytochrome C antibody is un-conjugated
(16), (9), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Immunoprecipitation (IP), Western Blotting (WB)
(187), (78), (60), (46), (41), (39), (26), (18), (14), (11), (11), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 10 references available
ProductDetails: Supplier Login to see New
ProductDetails: Supplier Product Number Login to see New
Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide corresponding to residues surrounding amino acid 70 of rat cytochrome c
Isotype IgG
Specificity Detects 15 kDa cytochrome c in samples from human/mouse/rat origins
Purification Affinity purified
Alternative Name Cytochrome C (CYCS Antibody Abstract)
Background Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases
Synonyms: CYCS, CYC
Gene ID 25310
NCBI Accession NP_036972
Research Area Apoptosis/Necrosis, Metabolism
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes The antibody can be used for Western blotting (0.5-4 µg/mL) and immunoprecipitation (10-20 µg/mL).
However the optimal conditions should be determined individually.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Cytochrome C antibody (Cytochrome C, Somatic) (ABIN222880) Western blot analysis of cytochrome c in Jurkat (left lane) and 3T3 (right lane) cell...
Product cited in: Hurst-Kennedy, Zhong, Gupta et al.: "24R,25-Dihydroxyvitamin D3, lysophosphatidic acid, and p53: A signaling axis in the inhibition of phosphate-induced chondrocyte apoptosis." in: The Journal of steroid biochemistry and molecular biology, 2010 (PubMed).

Gallentine, Hunnicutt, Husain: "Levetiracetam in children with refractory status epilepticus." in: Epilepsy & behavior : E&B, 2008 (PubMed).

Lan, Gorke, Rau et al.: "Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 7, pp. 4926-35, 2008 (PubMed).

Shimamura, Fujisawa, Husain et al.: "Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 7, pp. 4656-65, 2008 (PubMed).

Zhao, Chen, Lu et al.: "TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 11, pp. 4133-41, 2008 (PubMed).

Crowe, Turpin, Ke et al.: "Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity." in: Endocrinology, Vol. 149, Issue 5, pp. 2546-56, 2008 (PubMed).

Chen, Baydoun, Xu et al.: "Lysophosphatidic acid protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 1, pp. 135-45, 2008 (PubMed).

Kuhn, Chen, Voorhees et al.: "Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma." in: Blood, Vol. 110, Issue 9, pp. 3281-90, 2007 (PubMed).

Machiya, Shibata, Yamauchi et al.: "Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure." in: American journal of respiratory cell and molecular biology, Vol. 36, Issue 4, pp. 418-26, 2007 (PubMed).

Turpin, Lancaster, Darby et al.: "Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance." in: American journal of physiology. Endocrinology and metabolism, Vol. 291, Issue 6, pp. E1341-50, 2006 (PubMed).

Catalog No. ABIN222880
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?