Cytochrome C, Somatic (CYCS) antibody

Antigen: Cytochrome C, Somatic (CYCS)

Synonyms: cycs, CYCS, CYC, HCS, THC4, cyc, hcs, cyct, MGC75709, MGC89066, DKFZp468F1016, MGC128356, CYCSA, MGC93634, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, bln, bs30f07.y1, cyt c-d, cyt-c-d, cyt.c, cytochrome c, ms(2)04445, pDMc02, DmelCG13263, CG13263, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, cyt c-p, cyt-c-p, l(2)SH1590, pDMc01, DmelCG17903, CG17903

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB), Immunoprecipitation (IP)

Catalog no.: ABIN222880

Additional Information

Alternative name: Cytochrome c

Gene ID: 25310

Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 70 of rat cytochrome c

Format: Purified

Description: 100 ug purified rabbit polyclonal antibody. Detects 15 kDa cytochrome c in samples from human/mouse/rat origins. Tested in Western blot analysis and immunoprecipitation. Synonyms: Cytochrome c Polyclonal, Anti-Cytochrome c, Cytochrome c antibody, Cytochrome c apoptosis assay kit, cytochrome c, cytochrome Synonyms: Cytochrome c Polyclonal, Anti-Cytochrome c, Cytochrome c antibody, Cytochrome c apoptosis assay kit, cytochrome c, cytochrome

Specificity: Detects 15 kDa cytochrome c in samples from human/mouse/rat origins

Synonyms: cycs, CYCS, CYC, HCS, THC4, cyc, hcs, cyct, MGC75709, MGC89066, DKFZp468F1016, MGC128356, CYCSA, MGC93634, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, bln, bs30f07.y1, cyt c-d, cyt-c-d, cyt.c, cytochrome c, ms(2)04445, pDMc02, DmelCG13263, CG13263, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, cyt c-p, cyt-c-p, l(2)SH1590, pDMc01, DmelCG17903, CG17903

Application Details

Application Notes: The antibody can be used for Western blotting (0.5-4 ug/ml) and immunoprecipitation (10-20 ug/ml). However, the optimal conditions should be determined individually.

Buffer: 100 ug (0.2 mg/ml) affinity purified rabbit anti-Cytochrome c polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Storage: Store at -20 o C. For long-term storage, aliquot and freeze at -70 o C. Avoid repeated freeze/defrost cycles Shelf Life: 12 Months

Research Area: Metabolism

Restrictions: For Research Use only

Images

Western blot analysis of cytochrome c in Jurkat (left lane) and 3T3 (right lane) cell lysates.

Publications

Publications: Turpin, Lancaster, Darby et al.: "Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance." in: American journal of physiology. Endocrinology and metabolism, Vol. 291, Issue 6, pp. E1341-50, 2006 (PubMed).

Machiya, Shibata, Yamauchi et al.: "Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure." in: American journal of respiratory cell and molecular biology, Vol. 36, Issue 4, pp. 418-26, 2007 (PubMed).

Kuhn, Chen, Voorhees et al.: "Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma." in: Blood, Vol. 110, Issue 9, pp. 3281-90, 2007 (PubMed).

Chen, Baydoun, Xu et al.: "Lysophosphatidic acid protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 1, pp. 135-45, 2008 (PubMed).

Crowe, Turpin, Ke et al.: "Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity." in: Endocrinology, Vol. 149, Issue 5, pp. 2546-56, 2008 (PubMed).

Zhao, Chen, Lu et al.: "TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 11, pp. 4133-41, 2008 (PubMed).

Gallentine, Hunnicutt, Husain: "Levetiracetam in children with refractory status epilepticus." in: Epilepsy & behavior : E&B, 2008 (PubMed).

Hurst-Kennedy, Zhong, Gupta et al.: "24R,25-Dihydroxyvitamin D3, lysophosphatidic acid, and p53: A signaling axis in the inhibition of phosphate-induced chondrocyte apoptosis." in: The Journal of steroid biochemistry and molecular biology, 2010 (PubMed).