anti-HSP70 antibody (Heat Shock Protein 70)

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Antigen
Synonyms
HSP70, HEAT SHOCK PROTEIN 70, HEAT SHOCK PROTEIN 70-7, HSC70-7, K9P8.5, K9P8_5, chloroplast heat shock protein 70-2, cpHsc70-2, F19K16.12, F19K16_12, LOC100305036, hsc70, CG31354, Hsp70Bb, hsp70B, hsp ... show more
HSP70, HEAT SHOCK PROTEIN 70, HEAT SHOCK PROTEIN 70-7, HSC70-7, K9P8.5, K9P8_5, chloroplast heat shock protein 70-2, cpHsc70-2, F19K16.12, F19K16_12, LOC100305036, hsc70, CG31354, Hsp70Bb, hsp70B, hsp70Bb-prime, DmelCG5834, CG5834, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY, hsc71, Hsp70, Hsp70-1, Hsp70.1, hsp68, Hsp110, irp94, HSPA1, HSP70B', HSPA6, ARABIDOPSIS HEAT SHOCK PROTEIN 70, ATHSP70, heat shock protein 70, hsp70-5 show less
Reactivity
Cow (Bovine), Hamster, Human, Monkey, Mouse (Murine), Rabbit, Rat (Rattus)
(578), (263), (261), (114), (111), (100), (98), (74), (65), (62), (61), (59), (55), (51), (50), (42), (40), (35), (33), (26), (25), (24), (22), (19), (19), (19), (11), (8), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(378), (303), (41), (18)
Clonality
Polyclonal
Conjugate
This HSP70 antibody is un-conjugated
(34), (33), (24), (21), (21), (19), (19), (19), (19), (19), (19), (19), (19), (19), (19), (19), (17), (7), (6), (5), (5), (5), (5), (5), (5), (5), (3), (2), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(648), (291), (263), (262), (252), (228), (95), (89), (55), (53), (28), (19), (16), (9), (6), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen Synthetic peptide surrounding amino acid 559 of human Hsc70
Blocking Peptide Blocking peptide for this product available: Heat Shock 70kDa Protein 8 (HSPA8) peptide (ABIN412786)
Isotype IgG
Specificity The antibody detects a 71 kDa Hsc70.
A ~40 kDa band can also be detected in human samples.
Purification Affinity purified
Alternative Name Hsp70 (HSP70 Antibody Abstract)
Background The 70 kDa heat shock cognate protein, Hsc70, is part of the Hsp70 family. The family includes both cognate members and highly inducible isoforms. Members of the Hsp70 family are molecular chaperones which are involved in many cellular functions such as protein folding, transport, maturation and degradation.
Synonyms: HSPA8, LAP1, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, MGC131511, MGC29929, NIP71
Gene ID 3312
UniProt P11142
Research Area Cancer, Heat Shock Proteins, Signaling
Application Notes Western blot analysis (0.5-4 μg/mL) and in Immunohistochemistry.
Jurkat cell lysate and mouse small intestine lysate can be used as positive controls.
However, the optimal conditions should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-Hsc70 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-HSP70 antibody (Heat Shock Protein 70) (ABIN222930) anti-Heat Shock Protein 70 (HSP70) antibody
Product cited in: Yim, Sun, Wu et al.: "Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 9, pp. 4412-7, 2010 (PubMed).

Sugita, Kongo, Shiba: "Molecular dissection of the butyrate action revealed the involvement of mitogen-activated protein kinase in cystic fibrosis transmembrane conductance regulator biogenesis." in: Molecular pharmacology, Vol. 66, Issue 5, pp. 1248-59, 2004 (PubMed).

Catalog No. ABIN222930
$319.00
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