Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) antibody

Antigen: Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6)

Synonyms: MCH2, Mch2, mCASP-6, MGC93335, xCaspase-6, mch2, caspase-6, CASP6, MGC127633, zgc:112960, casp6

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Catalog no.: ABIN223017

Additional Information

Alternative name: Caspase-6

Gene ID: 83584

Immunogen: Synthetic peptide mapping to the C-terminus of rat caspase-6 large fragment

Format: Affinity-purified

Description: 100 ug affinity purified rabbit polyclonal antibody. Reacts with human/mouse/rat. Perform well in Western blotting. Synonyms: Caspase-6 Polyclonal Antibody, Anti Caspase-6 polyclonal antibody, Caspase-6 antibody, caspase antibody, caspase-6, active caspase-6, cleaved caspase-6, VEID, anti-caspase-6, procaspase-6, lamin A Synonyms: Caspase-6 Polyclonal Antibody, Anti Caspase-6 polyclonal antibody, Caspase-6 antibody, caspase antibody, caspase-6, active caspase-6, cleaved caspase-6, VEID, anti-caspase-6, procaspase-6, lamin A

Application Details

Application Notes: The antibody can be used for Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate tissue lysate can be used as a positive controls.

Buffer: 100 ug (0.2 mg/ml) rabbit anti-caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01 thimerosal.

Storage: Store at -20 o C. For long-term storage, aliquot and freeze at -70 o C. Avoid repeated freeze/defrost cycles Shelf Life: 12 Months

Research Area: Apoptosis/Necrosis

Restrictions: For Research Use only

Images

Western blot analysis of Caspase-6 expression rat kidney tissue lysate. Both full length and the cleaved large fragment have been detected.

Publications

Nikolaev, McLaughlin, OLeary et al.: "APP binds DR6 to trigger axon pruning and neuron death via distinct caspases." in: Nature, Vol. 457, Issue 7232, pp. 981-9, 2009 (PubMed).

Product: Vohra, Sasaki, Miller et al.: "Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13729-38, 2010 (PubMed).