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Perforin 1 antibody (Perforin 1 (Pore Forming Protein))

Details for Product anti-PRF1 Antibody No. ABIN223034, Supplier: Login to see New
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Mouse (Murine), Rat (Rattus)
(150), (39), (21), (6), (1), (1)
(97), (75), (18)
This Perforin 1 antibody is un-conjugated
(19), (10), (10), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Western Blotting (WB)
(84), (65), (35), (34), (34), (27), (23), (21), (20), (9), (6), (5), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Immunogen Recombinant rat perforin
Isotype IgG
Purification Affinity purified
Alternative Name Perforin (PRF1 Antibody Abstract)
Background Perforin (Pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte (CTL). It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL which represents an important mechanism in the immune defense against tumors and virus infection.
Synonyms: PFP, P1 , FLH2 , HPLH2, PRF1, Cytolysin , MGC65093
Gene ID 50669
Research Area Immunology, Innate Immunity, Adaptive Immunity, Inflammation
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes The antibody can be used for Western blot analysis (0.5-4 µg/mL).
However the optimal conditions should be determined individually.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Perforin 1 antibody (Perforin 1 (Pore Forming Protein)) (ABIN223034) Western blot analysis of Perforin in rat kidney glomerulars.
Product cited in: Dulphy, Haas, Busson et al.: "An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 2227-37, 2008 (PubMed).

Catalog No. ABIN223034

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