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Fas (TNFRSF6) Associated Factor 1 (FAF1) antibody

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Antigen
Synonyms faf1, MGC53741, MGC80303, FAF1, zgc:55752, wu:fc25h12, HFAF1s, UBXD12, UBXN3A, hFAF1, AA408698, Dffrx, Fam
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(77), (41), (40), (2), (2), (1), (1)
Host
Rabbit
(61), (16)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(62), (23), (18), (11), (7), (5), (5), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide corresponding to residues surrounding amino acid 640 of human FAF1
Blocking Peptide Blocking peptide for this product available: ABIN412729
Isotype IgG
Purification Affinity purified
Alternative Name FAF1 (FAF1 Antibody Abstract)
Background FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD, FADD, and RIP, FAF1 lacks a DDH (Death domain homologous region) and cannot induce apoptosis independent of Fas activation.
Synonyms: FAF1 (CT), Fas-associated protein 1, hFAF1, HFAF1s, TNFRSF6, TNFRSF6 associated factor 1 antibody, FAF1
Gene ID 11124
UniProt Q9UNN5
Research Area Apoptosis/Necrosis
Application Notes Western blotting (0.5-4 μg/mL) and in Immunoprecipitation and Immunohistochemistry.
Rat kidney cell lysate can be used as a positive control.
However, the optimal conditions should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-FAF1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibody (ABIN223070) Western blot analysis of FAF1 in rat kidney tissue extract
Product cited in: Altomare, Menges, Pei et al.: "Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 9, pp. 3420-5, 2009 (PubMed).

Catalog No. ABIN223070
$297.00
Plus shipping costs $45.00

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