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Details for Product No. ABIN223076

Cytochrome C, Somatic (CYCS) antibody

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Antigen
Synonyms
CYC, HCS, THC4, cytc, CYCSA, CYCS, ENSMUSG00000058927, cyc, zgc:86706, wu:fk52b01, cyct, hcs, cycs, CG13263, Cyt C, Cyt c, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, Dmel\\CG13263, bln, bs30f07.y1, cyt ... show more
Reactivity
»Alternatives Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 6 references available
Catalog no. ABIN223076
Quantity 100 µg
Price
269.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen Rat cytochrome c
Isotype IgG
Purification Affinity purified
Alternative Name Cytochrome c
Background Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.
Gene ID 6978725
Research Area Apoptosis/Necrosis, Metabolism, Cytochrome c
Application Notes The antibody can be used for Western blotting (0.5-4 µg/mL).
However the optimal conditions should be determined individually. Rat kidney lysate can be used as a positive control.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Product cited in: Machiya, Shibata, Yamauchi et al.: "Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure." in: American journal of respiratory cell and molecular biology, Vol. 36, Issue 4, pp. 418-26, 2007 (PubMed).

Kuhn, Chen, Voorhees et al.: "Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma." in: Blood, Vol. 110, Issue 9, pp. 3281-90, 2007 (PubMed).

Wang, Shen, Gao et al.: "Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats." in: Stroke; a journal of cerebral circulation, Vol. 39, Issue 3, pp. 983-90, 2008 (PubMed).

Zhao, Chen, Lu et al.: "TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 11, pp. 4133-41, 2008 (PubMed).

Lan, Gorke, Rau et al.: "Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 7, pp. 4926-35, 2008 (PubMed).

Katz, Morris, Trupin et al.: "Disability in valued life activities among individuals with systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 59, Issue 4, pp. 465-73, 2008 (PubMed).

Alternatives for antigen "Cytochrome C, Somatic (CYCS)", type "Antibodies"
Hosts (98), (78), (7), (4)
Reactivities (119), (73), (69), (40), (22), (19), (16), (13), (12), (9), (9), (7), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (133), (59), (41), (41), (31), (28), (21), (21), (10), (10), (6), (6), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Conjugates (15), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (8), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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