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Cytochrome C, Somatic (CYCS) antibody

Details for Product No. ABIN223076
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Antigen
Synonyms
CYC, HCS, THC4, cytc, CYCSA, CYCS, ENSMUSG00000058927, cyc, zgc:86706, wu:fk52b01, cyct, hcs, cycs, CG13263, Cyt C, Cyt c, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, Dmel\\CG13263, bln, bs30f07.y1, cyt ... show more
CYC, HCS, THC4, cytc, CYCSA, CYCS, ENSMUSG00000058927, cyc, zgc:86706, wu:fk52b01, cyct, hcs, cycs, CG13263, Cyt C, Cyt c, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, Dmel\\CG13263, bln, bs30f07.y1, cyt c, cyt c-d, cyt-c-d, cyt.c, cytochrome c, dc3, ms(2)04445, pDMc02, CG17903, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, Dmel\\CG17903, cyt c-p, cyt-c-p, cyt-c2, dc4, pDMc01 show less
Reactivity
Rat (Rattus)
(112), (69), (65), (32), (20), (14), (13), (12), (12), (7), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(100), (63), (7), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(128), (52), (33), (33), (32), (24), (17), (13), (11), (10), (6), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
Quantity 100 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN223076
269.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Rat cytochrome c
Isotype IgG
Purification Affinity purified
Alternative Name Cytochrome c
Background Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.
Gene ID 6978725
Research Area Apoptosis/Necrosis, Metabolism, Cytochrome c
Application Notes The antibody can be used for Western blotting (0.5-4 µg/mL).
However the optimal conditions should be determined individually. Rat kidney lysate can be used as a positive control.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
anti-Cytochrome C, Somatic (CYCS) antibody Western blot analysis of cytochrome c expression in rat kidney tissue lysate.
Product cited in: Machiya, Shibata, Yamauchi et al.: "Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure." in: American journal of respiratory cell and molecular biology, Vol. 36, Issue 4, pp. 418-26, 2007 (PubMed).

Kuhn, Chen, Voorhees et al.: "Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma." in: Blood, Vol. 110, Issue 9, pp. 3281-90, 2007 (PubMed).

Wang, Shen, Gao et al.: "Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats." in: Stroke; a journal of cerebral circulation, Vol. 39, Issue 3, pp. 983-90, 2008 (PubMed).

Zhao, Chen, Lu et al.: "TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 11, pp. 4133-41, 2008 (PubMed).

Lan, Gorke, Rau et al.: "Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 7, pp. 4926-35, 2008 (PubMed).

General Katz, Morris, Trupin et al.: "Disability in valued life activities among individuals with systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 59, Issue 4, pp. 465-73, 2008 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN223076
269.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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