Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae) (FIS1) antibody

Details for Product No. ABIN223209
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Antigen
Synonyms TTC11, Ttc11, 2010003O14Rik
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(38), (17), (17), (11), (11), (11)
Host
Rabbit
(29), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
(28), (10), (10), (9), (7), (6), (6), (5), (1)
Pubmed 5 references available
Quantity 100 µL
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Catalog No. ABIN223209
291.50 $
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Immunogen Synthetic peptide surrounding AA 143 of human fis1
Isotype IgG
Purification Affinity purified
Alternative Name fis1
Background Hfis1 is a novel molecule that was discovered as part of the mammalian fission machinery. fis 1 has been suggested to play a role in regulation of the fission processes that might be involved in apoptotic mechanisms.
Gene ID 51024
Application Notes The antibody has been used in Western blotting (1:100-500), immunoprecipitation (1:50-200),
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 20 % glycerol, 0.2 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Product cited in: Wasiak, Zunino, McBride: "Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death." in: The Journal of cell biology, Vol. 177, Issue 3, pp. 439-50, 2007 (PubMed).

Karbowski, Neutzner, Youle: "The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division." in: The Journal of cell biology, Vol. 178, Issue 1, pp. 71-84, 2007 (PubMed).

Thomas, McCoy, Blackinton et al.: "DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy." in: Human molecular genetics, Vol. 20, Issue 1, pp. 40-50, 2010 (PubMed).

Jheng, Tsai, Guo et al.: "Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle." in: Molecular and cellular biology, Vol. 32, Issue 2, pp. 309-19, 2011 (PubMed).

General Sandebring, Thomas, Beilina et al.: "Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1." in: PLoS ONE, Vol. 4, Issue 5, pp. e5701, 2009 (PubMed).

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