Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae) (FIS1) antibody

Details for Product No. ABIN223210
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Antigen
Synonyms TTC11, Ttc11, 2010003O14Rik
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(1), (1), (1)
Host
Rabbit
(1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(1), (1), (1), (1)
Pubmed 2 references available
Quantity 100 μg
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Immunogen Synthetic peptide surrounding amino acid 143 of human Fis1
Isotype IgG
Purification Affinity purified
Background HFis1 is a novel molecule that was discovered as part of the mammalian fission machinery. Fis 1 has been sμggested to play a role in regulation of the fission processes that might be involved in apoptotic mechanisms.
Synonyms: hFis1 , TTC11 , H_NH0132A01.6 , CGI-135
Gene ID 51024
UniProt Q9Y3D6
Application Notes Western blotting (1-4 µg/mL).
Per research's feedback, the antibody can also be used in immunofluorescence.
However the optimal concentrations should be determined individually.
The antibody recognizes fis1 of human, mouse, and rat origins.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
anti-Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae) (FIS1) antibody Western blot analysis of Fis-1 expression with Jurkat Cell lysates.
Product cited in: Thomas, McCoy, Blackinton et al.: "DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy." in: Human molecular genetics, Vol. 20, Issue 1, pp. 40-50, 2010 (PubMed).

Javadov, Rajapurohitam, Kili? et al.: "Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition." in: Basic research in cardiology, Vol. 106, Issue 1, pp. 99-109, 2010 (PubMed).

Validation Images
Catalog No. ABIN223210
319.00 $
Plus shipping costs $45.00
Quantity
Price
100 μg
319.00 $

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