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Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae) (FIS1) antibody

Details for Product No. ABIN223210, Supplier: Log in to see
Antigen
  • TTC11
  • Ttc11
  • 2010003O14Rik
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1
1
1
Host
Rabbit
1
Clonality
Polyclonal
Application
Western Blotting (WB)
1
1
1
1
Supplier
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Immunogen Synthetic peptide surrounding amino acid 143 of human Fis1
Blocking Peptide Blocking peptide for this product available: ABIN412734
Isotype IgG
Specificity The antibody recognizes Fis1 of human, mouse, and rat origins.
Purification Affinity purified
Background HFis1 is a novel molecule that was discovered as part of the mammalian fission machinery. Fis 1 has been sμggested to play a role in regulation of the fission processes that might be involved in apoptotic mechanisms.
Synonyms: hFis1 , TTC11 , H_NH0132A01.6 , CGI-135
Gene ID 51024
UniProt Q9Y3D6
Pathways
Application Notes Western blotting (1-4 μg/mL). Immunofluorescence.
However, the optimal concentrations should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae) (FIS1) antibody (ABIN223210) Western blot analysis of Fis-1 expression with Jurkat Cell lysates.
Product cited in: Jheng, Tsai, Guo et al.: "Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle." in: Molecular and cellular biology, Vol. 32, Issue 2, pp. 309-19, 2011 (PubMed).

Ganapathy, Perry, Tawfik et al.: "Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5551-8, 2011 (PubMed).

Thomas, McCoy, Blackinton et al.: "DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy." in: Human molecular genetics, Vol. 20, Issue 1, pp. 40-50, 2010 (PubMed).

Javadov, Rajapurohitam, Kili? et al.: "Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition." in: Basic research in cardiology, Vol. 106, Issue 1, pp. 99-109, 2010 (PubMed).