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Details for Product No. ABIN223215

serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1) (SERPINH1) antibody

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Synonyms HSP47, AsTP3, CBP1, CBP2, OI10, PPROM, RA-A47, SERPINH2, gp46, BERF-1, Cbp1, Cbp2, Hsp47, J6, Serpinh2, colligin, astp3, cbp1, cbp2, hsp47, pig14, pprom, ra-a47, serpinh2, SERPINH1, DKFZp468B197
»Alternatives Human, Mouse (Murine), Rat (Rattus)
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Blocking Antibody (Inhibition)
Pubmed 1 reference available
Catalog no. ABIN223215
Quantity 100 µg
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide surrounding AA 407 of human HSP47
Isotype IgG
Purification Affinity purified
Alternative Name Hsp47
Background Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. HSP47 is a molecule expressed constitutively in cells that synthesizes collagen. HSP47 is a procollagen-specific molecular chaperon that resides in the endoplasmic reticulum of procollagen-producing cells and is essential for secretion of procollagen from cells. Significantly, HSP47 plays a vital role in folding and assembling collagen. HSP47 is also known as colligin 1, serpinh1, collagen-binding protein 1 (CBP1) and gp46. The human HSP 47 gene encodes a 47 kDa protein.
Gene ID 12406
Research Area Signaling, Heat Shock Proteins
Application Notes The antibody can be used in Western blotting (0.5-4 µg/mL).
Based on researcher's feedback, it can also be used in immunoprecipitation (10-20 µg/mL) and immunohistochemistry (10-20 µg/mL).
However the optimal concentrations should be determined individually.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Product cited in: Cheng, Pollock, Mahimkar et al.: "Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 11, pp. 1898-900, 2006 (PubMed).

Alternatives for antigen "serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1) (SERPINH1)", type "Antibodies"
Hosts (38), (14)
Reactivities (48), (26), (21), (6), (2), (2), (1), (1)
Applications (39), (15), (13), (12), (10), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (3), (2), (2), (2), (1), (1), (1)