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Voltage-Dependent Anion Channel 1 (VDAC1) antibody

Details for Product No. ABIN223288
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Antigen
Synonyms PORIN, VDAC-1, Vdac5, AL033343, fa13f11, zgc:85830, wu:fa13f11, 5076, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1, ATVDAC1, T22N4.9, T22N4_9, voltage dependent anion channel 1, vdac1, VDAC1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Rabbit, Pig (Porcine)
(83), (35), (33), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(46), (43)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Western Blotting (WB)
(87), (50), (38), (26), (14), (4), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN223288
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide surrounding AA 189 of human VDAC
Isotype IgG
Specificity Detects approx. 31 kDa VDAC in samples from human/mouse/rat/bovine/rabbit/pig origins
Purification Affinity purified
Alternative Name VDAC/Porin
Background The Voltage-Dependent Anion Channel (VDAC or mitochondrial Porin)I is an outer membrane mitochondrial protein. The VDAC protein is thought to form the major pores through which adenine nucleotides are transferred through the outer mitochondrial membrane. VDAC has also been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, ANT, and CypD is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis.
Gene ID 7416
Research Area Signaling, Metabolism, Organelles, Apoptosis/Necrosis
Application Notes The antibody can be used for Western blotting (0.5-4 µg/mL).
However the optimal concentrations should be determined individually.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
anti-Voltage-Dependent Anion Channel 1 (VDAC1) antibody Western blot analysis of VDAC/Porinwith 3T3 cell lysate.
Product cited in: Bortner, Scoltock, Sifre et al.: "Osmotic stress resistance imparts acquired anti-apoptotic mechanisms in lymphocytes." in: The Journal of biological chemistry, Vol. 287, Issue 9, pp. 6284-95, 2012 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN223288
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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