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Details for Product No. ABIN223293

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibody

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Antigen
Synonyms ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM, Cyp19, Cyp19a, p450arom, Aromatase, P450AROM, Ar, ArKO, Int-5, Int5, CYP19P1, CYP19A1, P450 arom, aro, cyp19, cyp19a, p450arom-A
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Pig (Porcine), Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN223293
Quantity 100 µg
Price
324.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide surrounding AA 385 of human Aromatase
Isotype IgG
Purification Affinity purified
Alternative Name Aromatase
Background Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, fertility, and carcinogenesis. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.
Gene ID 1588
Research Area Cancer, Endocrine system, Enzymes
Application Notes The antibody can be used for Western blotting (0.5-4 µg/mL).
Based on researcher's feedback, the antibody can also be used in immunohistochemistry (10-20 µg/mL).
However the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Product cited in: Sun, Yan, Jacobson et al.: "Contribution of epoxyeicosatrienoic acids to flow-induced dilation in arteries of male ERalpha knockout mice: role of aromatase." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 293, Issue 3, pp. R1239-46, 2007 (PubMed).

Bukulmez, Hardy, Carr et al.: "Inflammatory status influences aromatase and steroid receptor expression in endometriosis." in: Endocrinology, Vol. 149, Issue 3, pp. 1190-204, 2008 (PubMed).

Hirayama, Sawai, Moriyasu et al.: "Excess estrogen sulfoconjugation as the possible cause for a poor sign of parturition in pregnant cows carrying somatic cell clone fetuses." in: Reproduction (Cambridge, England), Vol. 136, Issue 5, pp. 639-47, 2008 (PubMed).

Yonezawa, Higashi, Yoshioka et al.: "Distribution of aromatase and sex steroid receptors in the baculum during the rat life cycle: effects of estrogen during the early development of the baculum." in: Biology of reproduction, Vol. 85, Issue 1, pp. 105-12, 2011 (PubMed).

Alternatives for antigen "Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1)", type "Antibodies"
Hosts (75), (21), (8)
Reactivities (90), (55), (45), (40), (39), (37), (16), (10), (7), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (72), (37), (30), (27), (17), (12), (6), (3), (1), (1)
Conjugates (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Epitopes (20), (7), (6), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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