Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibody

Details for Product No. ABIN223293
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Synonyms CYP19, CYP19A1, ARO, ARO1, CPV1, CYAR, CYPXIX, P-450AROM, Aromatase, Cyp19, Cyp19a, p450arom, CYP19P1, Ar, ArKO, Int-5, Int5, P450AROM, P450 arom, aro, cyp19, cyp19a, p450arom-A
Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Pig (Porcine), Chicken
(116), (48), (34), (16), (8), (7), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
(78), (25), (20)
(4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Western Blotting (WB), Immunohistochemistry (IHC)
(100), (44), (34), (27), (20), (16), (12), (8), (4), (4), (4), (4), (1)
Pubmed 4 references available
Quantity 100 μg
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Request Want additional data for this product?

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Catalog No. ABIN223293
363.00 $
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Immunogen Synthetic peptide surrounding AA 385 of human Aromatase
Isotype IgG
Purification Affinity purified
Alternative Name Aromatase
Background Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, fertility, and carcinogenesis. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.
Gene ID 1588
Research Area Cancer, Endocrine system, Enzymes
Application Notes The antibody can be used for Western blotting (0.5-4 µg/mL).
Based on researcher's feedback, the antibody can also be used in immunohistochemistry (10-20 µg/mL).
However the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibody Western blot analysis of Aromatase in human brain cell lysate.
Product cited in: Yonezawa, Higashi, Yoshioka et al.: "Distribution of aromatase and sex steroid receptors in the baculum during the rat life cycle: effects of estrogen during the early development of the baculum." in: Biology of reproduction, Vol. 85, Issue 1, pp. 105-12, 2011 (PubMed).

Hirayama, Sawai, Moriyasu et al.: "Excess estrogen sulfoconjugation as the possible cause for a poor sign of parturition in pregnant cows carrying somatic cell clone fetuses." in: Reproduction (Cambridge, England), Vol. 136, Issue 5, pp. 639-47, 2008 (PubMed).

Bukulmez, Hardy, Carr et al.: "Inflammatory status influences aromatase and steroid receptor expression in endometriosis." in: Endocrinology, Vol. 149, Issue 3, pp. 1190-204, 2008 (PubMed).

Sun, Yan, Jacobson et al.: "Contribution of epoxyeicosatrienoic acids to flow-induced dilation in arteries of male ERalpha knockout mice: role of aromatase." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 293, Issue 3, pp. R1239-46, 2007 (PubMed).

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