Histone Deacetylase 10 (HDAC10) antibody

Antigen: Histone Deacetylase 10 (HDAC10)

Synonyms: MGC149722, DKFZp761B039, Hd10, AW548891, HDAC10, MGC139128, fd19e10, wu:fd19e10, MGC115178, histone deacetylase 10

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rabbit

Conjugate: Un-conjugated

Application: Please enquire

Catalog no.: ABIN223305

Additional Information

Alternative name: HDAC10

Gene ID: 83933

Immunogen: Synthetic peptide near the N-terminus of human HDAC-10 (ID# BV-73)

Format: Purified

Description: 100 ug rabbit anti-HDAC-10 polyclonal antibody. Synonyms: HDAC10 Polyclonal Antibody, Anti-HDAC10 antibody, HDAC10 antibody, Anti-HDAC10, HDAC10, HDAC, HDACs, Histone deacetylase, HAT, histone acetyltransferase Synonyms: HDAC10 Polyclonal Antibody, Anti-HDAC10 antibody, HDAC10 antibody, Anti-HDAC10, HDAC10, HDAC, HDACs, Histone deacetylase, HAT, histone acetyltransferase

Application Details

Application Notes: The antibody can be used in Western blotting (0.5-4 ug/ml), However, the optimal concentrations should be determined individually. Blocking peptide is available separately.

Buffer: 100 ug (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Storage: Store at -20 o C. For long term storage, aliquot and freeze at

Research Area: DNA/RNA, Transcription Factors

Restrictions: For Research Use only

Images

Western blot analysis of HDAC-10 expression. Lane Jurkat Cells Lane Mouse Intestine Lane Rat Brain

Publications

Product: Bali, Pranpat, Bradner et al.: "Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors." in: The Journal of biological chemistry, Vol. 280, Issue 29, pp. 26729-34, 2005 (PubMed).

Fiskus, Rao, Fernandez et al.: "Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells." in: Blood, Vol. 112, Issue 7, pp. 2896-905, 2008 (PubMed).

Ai, Wang, Dar et al.: "HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 12, pp. 1963-72, 2009 (PubMed).