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Calcitonin-Related Polypeptide alpha (CALCA) antibody

Antigen

Calcitonin-Related Polypeptide alpha (CALCA)

Synonyms CALCA, CALC3, MGC152154, CT, KC, CGRP, CALC1, CGRP1, CGRP-I, MGC126648, CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, HsT2645, 2410002I16Rik, 5830420C16Rik, CALC, calcitonin, calca, ci-ct
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Mouse (Murine), Rat (Rattus)

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Neutralization (Neut)
1 reference available
Catalog no. ABIN223557
Quantity 100 ug  (0.5 mg/mL)  (Variants)
Price 269.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name KC
Gene ID 206687
Immunogen E. coli-expressed rat KC
Format Liquid
Isotype IgG
Description KC, a homolog of human and hamster gro/MGSA, is a 72-amino acid CXC chemokine originally cloned from rat macrophages and lung tissue. It is the mediator for recruitment and activation of netrophils in rat lung inflammation models. Expression of KC can be upregulated by LPS and IL-1β stimulation. IFN-g blocks LPS-induced expression of KC.

Application Details

Application Notes The antibody can be used for Western blot analysis (0.5-4 ug/ml), Immunoprecipitation (3-5 ug/ml), and immunohistochemistry (10-20 ug/ml). However, the optimal conditions should be determined individually.
Handling Advice The antibody solution should be gently mixed before use.
Concentration 0.5 mg/mL
Purification Affinity purified
Buffer phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Preservative Thimerosal
Storage -20 °C
Expiry Date 12 months
Restrictions For Research Use only

Publications

Product Thaxton, Romero, Sharma: "TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 1144-54, 2009 (PubMed).

Alternatives

Alternatives for antigen "Calcitonin-Related Polypeptide alpha (CALCA)", type "Antibodies"
Hosts Rabbit (122), Mouse (19), Goat (8), Sheep (3), Guinea Pig (2), Chicken (1)
Reactivities Human (123), Dog (Canine) (22), Rat (Rattus) (21), Mouse (Murine) (14), Monkey (4), Pig (Porcine) (4), Sheep (Ovine) (4), Hamster (3), Mammalian (3), Chicken (2), Horse (Equine) (1), Rabbit (1), Reptile (1)
Applications Western Blotting (WB) (47), ELISA (44), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (42), Immunofluorescence (IF) (41), Immunohistochemistry (IHC) (32), Immunohistochemistry (Frozen Sections) (IHC (fro)) (21), Radioimmunoassay (RIA) (15), Immunocytochemistry (ICC) (9), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (8), Enzyme Immunoassay (EIA) (4), Electrophoresis (EP) (3), Immunoprecipitation (IP) (3), ELISA (Capture) (2), Immunoelectron Microscopy (IEM) (2), Blocking Antibody (Inhibition) (1), ELISA (Detection) (1), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (ffpe)) (1)
Conjugates Biotin (9), FITC (7), HRP (3), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
Epitopes C-Term (21), AA 1-32 (6), Internal Region (3), Center (2), C-Term,AA 103-132 (1), Internal Region,AA 63-91 (1), Precurser (1), Precursor (1)