Chemokine (C-X-C Motif) Ligand 1 (CXCL1) antibody

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Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(126), (76), (75), (2), (2), (2)
Host
Rabbit
(189), (27), (18), (3), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(36), (11), (7), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(176), (136), (47), (29), (23), (14), (13), (12), (12), (10), (8), (4), (4), (2), (2), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen E. coli-expressed human SDF-1alpha
Isotype IgG
Purification Affinity purified
Alternative Name SDF-1a
Background SDF-1α (stromal cell-derived factor-α), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Synonyms: SDF-1a, SDF 1a, SDF 1alpha, SDF 1 alpha, SDF -1, SDF, Stromal cell-derived factor 1,DF-1, C-X-C motif chemokine 12, Pre-B cell growth-stimulating factor, PBSF,SDF-1-alpha
Gene ID 6387
NCBI Accession NP_001029058
Application Notes Western blot analysis (0.5-1 μg/mL). Immunofluorescence and Neutralization (2-10 μg/mL).
However, the optimal conditions should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-human SDF-1α polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol and 0.01 thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Chemokine (C-X-C Motif) Ligand 1 (CXCL1) antibody (ABIN223587) Western blot analysis of with ug His-tagged recombinant human SDF-1 alpha protein
Product cited in: di Tomaso, Snuderl, Kamoun et al.: "Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape." in: Cancer research, Vol. 71, Issue 1, pp. 19-28, 2011 (PubMed).

Kondo, Shintani, Shibata et al.: "Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 1, pp. 61-6, 2008 (PubMed).

Catalog No. ABIN223587
$297.00
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