Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) antibody

Details for Product No. ABIN223587, Supplier: Log in to see
Antigen
  • CXCL1
  • MGSA
  • CINC-1
  • Gro1
  • Fsp
  • KC
  • Mgsa
  • N51
  • Scyb1
  • gro
  • GRO
  • SCYB1
  • Gro
  • FSP
  • GRO1
  • GROa
  • MGSA-a
  • NAP-3
  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • chemokine (C-X-C motif) ligand 2
  • chemokine (C-X-C motif) ligand 1
  • CXCL1
  • CXCL2
  • Cxcl1
  • GRO1
Alternatives
anti-Rat (Rattus) Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) antibody for Immunofluorescence (fixed cells)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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102
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3
1
1
1
1
Host
Rabbit
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38
24
15
3
1
Clonality
Polyclonal
Conjugate
Un-conjugated
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13
10
7
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6
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3
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2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
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132
56
40
16
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15
13
13
8
8
5
5
4
4
2
1
1
Options
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Immunogen E. coli-expressed human SDF-1alpha
Isotype IgG
Purification Affinity purified
Alternative Name SDF-1a (CXCL1 Antibody Abstract)
Background SDF-1α (stromal cell-derived factor-α), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Synonyms: SDF-1a, SDF 1a, SDF 1alpha, SDF 1 alpha, SDF -1, SDF, Stromal cell-derived factor 1,DF-1, C-X-C motif chemokine 12, Pre-B cell growth-stimulating factor, PBSF,SDF-1-alpha
Gene ID 6387
NCBI Accession NP_001029058
Pathways Autophagy
Application Notes Western blot analysis (0.5-1 μg/mL). Based on researcher's feedback, it can also be used in immunofluorescence and neutralization (2-10 μg/mL). However, the optimal conditions should be determined individually.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-human SDF-1α polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol and 0.01 thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) antibody (ABIN223587) Western blot analysis of with ug His-tagged recombinant human SDF-1 alpha protein
Product cited in: Abdul-Muneer, Conte, Haldar, Long, Patel, Santhakumar, Overall, Pfister: "Traumatic brain injury induced matrix metalloproteinase2 cleaves CXCL12α (stromal cell derived factor 1α) and causes neurodegeneration." in: Brain, behavior, and immunity, 2016 (PubMed).

di Tomaso, Snuderl, Kamoun, Duda, Auluck, Fazlollahi, Andronesi, Frosch, Wen, Plotkin, Hedley-Whyte, Sorensen, Batchelor, Jain: "Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape." in: Cancer research, Vol. 71, Issue 1, pp. 19-28, 2011 (PubMed).

Kondo, Shintani, Shibata, Murakami, Murakami, Imaizumi, Kitagawa, Murohara: "Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 1, pp. 61-6, 2008 (PubMed).