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Chemokine (C-X-C Motif) Ligand 12 (CXCL12) antibody

Details for Product No. ABIN223587
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Antigen
Synonyms sdf1a, a-sdf1a, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, Pbsf, Scyb12, Sdf1, Tlsf, Tpar1, sdf-1, sdf1, xSDF-1, SDF-1
Reactivity
Human
(102), (53), (42), (26), (26), (14), (12), (1), (1)
Host
Rabbit
(94), (18), (12), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(21), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Western Blotting (WB), ELISA
(91), (71), (31), (20), (18), (11), (8), (7), (5), (4), (2), (1)
Pubmed 2 references available
Quantity 100 µg
Options
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Catalog No. ABIN223587
269.50 $
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Immunogen E. coli-expressed human SDF-1alpha
Isotype IgG
Purification Affinity purified
Alternative Name SDF-1alpha
Background SDF-1alpha (stromal cell-derived factor-alpha), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Gene ID 6387
Application Notes The antibody can be used for Western blot analysis (0.5-1 µg/mL).
Based on researcher's feedback, it can also be used in ELISA (2-3 µg/mL), and neutralization (2-10 µg/mL).
However the optimal conditions should be determined individually.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS pH 7.2, containing 30 % glycerol and 0.01 thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C/-80 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) antibody Western blot analysis of with ug His-tagged recombinant human SDF-1 alpha protein
Product cited in: Kondo, Shintani, Shibata et al.: "Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 1, pp. 61-6, 2008 (PubMed).

di Tomaso, Snuderl, Kamoun et al.: "Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape." in: Cancer research, Vol. 71, Issue 1, pp. 19-28, 2011 (PubMed).

Validation Images
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