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Sulfotransferase Family 1E, Estrogen-Preferring, Member 1 (SULT1E1) antibody

Details for Product No. ABIN233862, Supplier: Log in to see
Antigen
  • St1
  • EST
  • EST-1
  • ST1E1
  • STE
  • ESTSUL
  • Ste
Reactivity
Human, Rat (Rattus)
29
14
7
Host
Rabbit
23
13
Clonality
Polyclonal
Conjugate
Un-conjugated
1
Application
Western Blotting (WB)
23
9
7
5
5
2
1
Supplier
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Immunogen Synthetic peptide surrounding amino acid 195 of human Estrogen Sulfotransferase (EST)
Blocking Peptide Blocking peptide for this product available: ABIN412726
Isotype IgG
Specificity Detects 31 kDa Estrogen Sulfotransferase (EST) of human and rat origins.
Purification Affinity purified
Alternative Name Estrogen Sulfotransferase (SULT1E1 Antibody Abstract)
Background Mammalian EST sulfurylates the hydroxyl group of estrogenic steroids by transferring the sulfate from a cosubstrate adenosine 3'-phosphate-5'-phosphosulfate. Sulfurylated steroids do not bind to the estrogen receptor with high affinity and, therefore, are hormonally inactive. EST plays an important role in controlling the intracellular level of the receptor-active estrogens.
Synonyms: EST, EST-1 , MGC34459 , STE , SULT1E1
Gene ID 6783
UniProt P49888
Research Area Signaling, Metabolism, Enzymes
Application Notes Western blotting (0.5-4 μg/mL).
However, the optimal conditions should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti- Estrogen Sulfotransferase polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Sulfotransferase Family 1E, Estrogen-Preferring, Member 1 (SULT1E1) antibody (ABIN233862) Western blot analysis of Estrogen Sulfotransferase (EST) with Jurkat cell lysates (L...
Product cited in: Cole, Keum, Liu et al.: "Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 14, pp. 6222-7, 2010 (PubMed).