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Apolipoprotein D antibody (APOD)

Details for Product anti-APOD Antibody No. ABIN234325, Supplier: Login to see New
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(82), (36), (28), (1), (1)
(68), (22), (6), (2)
Clonality (Clone)
Monoclonal ()
This Apolipoprotein D antibody is un-conjugated
(6), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(73), (47), (26), (13), (12), (8), (6), (6), (1), (1)
Pubmed 11 references available
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Catalog number from supplier Login to see New
Quantity 0.2 mL
Shipping to United States ( )
Immunogen Apo D, a progesterone binding glycoprotein of 24, 000 dalton monomer molecular size
Clone 8CD6
Isotype IgG1
Specificity Apo D is localized to steroid-responsive tissues (adrenal cortex, ovary, endometrium, prostate and pituitary). Apocrine epithelium within axillary skin exhibited strongly positive staining for Apo D and peripheral nerves, pituitary and renal tubules were also immunoreactive. Apo D, a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma and was first isolated in large quantity as GCDFP-24, the major protein component of most human breast cyst fluids.
Characteristics MAb to Apolipoprotein D, Monoclonal antibody to Apolipoprotein D (Apo D), Tissue culture supernatant
Purification Protein A Chromatography. Ascites
Alternative Name Apolipoprotein D (Apo D) (APOD Antibody Abstract)
Research Area Metabolism
Application Notes Suitable for use in ELISA, Western blot and immunohistochemistry (>1:200, paraffin). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS.
Preservative Without preservative
Handling Advice Avoid multiple/freeze thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Thomas, Dean, Pavey et al.: "Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects: implications for the pathophysiology of psychiatric disorders." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 7, pp. 4066-71, 2001 (PubMed).

Kalman, McConathy, Araoz et al.: "Apolipoprotein D in the aging brain and in Alzheimer's dementia." in: Neurological research, Vol. 22, Issue 4, pp. 330-6, 2000 (PubMed).

Kolodny: "Niemann-Pick disease." in: Current opinion in hematology, Vol. 7, Issue 1, pp. 48-52, 2000 (PubMed).

Franz, Reindl, Patel et al.: "Increased expression of apolipoprotein D following experimental traumatic brain injury." in: Journal of neurochemistry, Vol. 73, Issue 4, pp. 1615-25, 1999 (PubMed).

Montpied, de Bock, Lerner-Natoli et al.: "Hippocampal alterations of apolipoprotein E and D mRNA levels in vivo and in vitro following kainate excitotoxicity." in: Epilepsy research, Vol. 35, Issue 2, pp. 135-46, 1999 (PubMed).

Navarro, Tolivia, Astudillo et al.: "Pattern of apolipoprotein D immunoreactivity in human brain." in: Neuroscience letters, Vol. 254, Issue 1, pp. 17-20, 1999 (PubMed).

Suresh, Yan, Patel et al.: "Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D." in: Journal of neurochemistry, Vol. 70, Issue 1, pp. 242-51, 1998 (PubMed).

Ong, He, Suresh et al.: "Differential expression of apolipoprotein D and apolipoprotein E in the kainic acid-lesioned rat hippocampus." in: Neuroscience, Vol. 79, Issue 2, pp. 359-67, 1997 (PubMed).

Zeng, Spielman, Vowels et al.: "A human axillary odorant is carried by apolipoprotein D." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 13, pp. 6626-30, 1996 (PubMed).

Flower: "The lipocalin protein family: a role in cell regulation." in: FEBS letters, Vol. 354, Issue 1, pp. 7-11, 1994 (PubMed).

Aspinall, Bentel, Horsfall et al.: "Differential expression of apolipoprotein-D and prostate specific antigen in benign and malignant prostate tissues." in: The Journal of urology, Vol. 154, Issue 2 Pt 1, pp. 622-8, 1995 (PubMed).

Catalog No. ABIN234325

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