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Apolipoprotein D (APOD) antibody

Details for Product No. ABIN234325
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Antigen
Synonyms APOD, apod, zgc:153593, AOPDGN, Apo-D, lipocalin
Reactivity
Human
(48), (34), (30), (24), (24), (12)
Host
Mouse
(42), (6), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(30), (20), (20), (13), (5), (3), (3), (1)
Pubmed 11 references available
Quantity 0.2 mL
Options
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Catalog No. ABIN234325
1,068.47 $
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Immunogen Apo D, a progesterone binding glycoprotein of 24, 000 dalton monomer molecular size
Clone 8CD6
Specificity Apo D is localized to steroid-responsive tissues (adrenal cortex, ovary, endometrium, prostate and pituitary). Apocrine epithelium within axillary skin exhibited strongly positive staining for Apo D and peripheral nerves, pituitary and renal tubules were also immunoreactive. Apo D, a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma and was first isolated in large quantity as GCDFP-24, the major protein component of most human breast cyst fluids.
Characteristics MAb to Apolipoprotein D, Monoclonal antibody to Apolipoprotein D (Apo D), Tissue culture supernatant
Purification Protein A Chromatography. Ascites
Alternative Name Apolipoprotein D (Apo D)
Research Area Metabolism
Application Notes Suitable for use in ELISA, Western blot and immunohistochemistry (>1:200, paraffin). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration ~1 mg/mL
Buffer PBS.
Handling Advice Avoid multiple/freeze thaw cycles.
Storage -20 °C
Storage Comment Store at -20°C.
General Aspinall, Bentel, Horsfall et al.: "Differential expression of apolipoprotein-D and prostate specific antigen in benign and malignant prostate tissues." in: The Journal of urology, Vol. 154, Issue 2 Pt 1, pp. 622-8, 1995 (PubMed).

Flower: "The lipocalin protein family: a role in cell regulation." in: FEBS letters, Vol. 354, Issue 1, pp. 7-11, 1994 (PubMed).

Zeng, Spielman, Vowels et al.: "A human axillary odorant is carried by apolipoprotein D." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 13, pp. 6626-30, 1996 (PubMed).

Ong, He, Suresh et al.: "Differential expression of apolipoprotein D and apolipoprotein E in the kainic acid-lesioned rat hippocampus." in: Neuroscience, Vol. 79, Issue 2, pp. 359-67, 1997 (PubMed).

Suresh, Yan, Patel et al.: "Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D." in: Journal of neurochemistry, Vol. 70, Issue 1, pp. 242-51, 1998 (PubMed).

Navarro, Tolivia, Astudillo et al.: "Pattern of apolipoprotein D immunoreactivity in human brain." in: Neuroscience letters, Vol. 254, Issue 1, pp. 17-20, 1999 (PubMed).

Montpied, de Bock, Lerner-Natoli et al.: "Hippocampal alterations of apolipoprotein E and D mRNA levels in vivo and in vitro following kainate excitotoxicity." in: Epilepsy research, Vol. 35, Issue 2, pp. 135-46, 1999 (PubMed).

Franz, Reindl, Patel et al.: "Increased expression of apolipoprotein D following experimental traumatic brain injury." in: Journal of neurochemistry, Vol. 73, Issue 4, pp. 1615-25, 1999 (PubMed).

Kolodny: "Niemann-Pick disease." in: Current opinion in hematology, Vol. 7, Issue 1, pp. 48-52, 2000 (PubMed).

Kalman, McConathy, Araoz et al.: "Apolipoprotein D in the aging brain and in Alzheimer's dementia." in: Neurological research, Vol. 22, Issue 4, pp. 330-6, 2000 (PubMed).

Thomas, Dean, Pavey et al.: "Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects: implications for the pathophysiology of psychiatric disorders." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 7, pp. 4066-71, 2001 (PubMed).

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