Cadherin 1 (CDH1) antibody

Antigen: Cadherin 1 (CDH1)

Synonyms: cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Clonality: Monoclonal (67A4)

Host: Mouse

Reactivity: Human

Application: Immunoprecipitation (IP), Immunohistochemistry (IHC)

Catalog no.: ABIN234423

Additional Information

Alternative name: E-Cadherin

Immunogen: Human breast carcinoma cell line T47D

Format: Purified, Lyophilized

Isotype: IgG1  (Matching secondary antibodies)

Clone: 67A4

Description: MAb to E-Cadherin Monoclonal Antibody to E-Cadherin

Specificity: E-Cadherin (also called cell CAM 120/180 or L-CAM) is a 123kDa molecule of the cadherin family which mediates Ca2+ dependent homotypic adhesion between epithelial cells. (1,2). Recognizes E-cadherin expressed on non-neuronal epithelial cells

Synonyms: cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Application Details

Application Notes: Immunoprecipitaion Immunohistochemistry Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Not applicable.

Purification: Protein A chromatography. Source: Ascites

Buffer: Lyophilized from PBS with 1mg/ml BSA.

Storage: Store lyophilized product at 2-8°C. After reconstitution, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage of the reconstituted product for up to one month at 2-8°C.Reconstitute with 1ml of distilled water.

Restrictions: For Research Use only

Publications

Publications: Geiger, Ayalon: "Cadherins." in: Annual review of cell biology, Vol. 8, pp. 307-32, 1993 (PubMed).

Nagafuchi, Shirayoshi, Okazaki et al.: "Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA." in: Nature, Vol. 329, Issue 6137, pp. 341-3, 1987 (PubMed).