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Chemokine (C-C Motif) Receptor 5 (CCR5) antibody

Antigen

Chemokine (C-C Motif) Receptor 5 (CCR5)
Synonyms CKR5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, FLJ78003, Ckr5, Cmkbr5, CCR5, CCR1-L, GPCR, MGC137803, CCR-5, AM4-7, CCR2, CCR5-L
Clonality Monoclonal (HEK-1-85a)
Host
Reactivity
Alternatives

Human
Application
Alternatives Flow Cytometry (FACS)
1 reference available
Catalog no. ABIN234550
Quantity 0.2mg  (Lot specific)
Price 548.67 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information
Application Details Publications Alternatives Secondary Antibodies back to top

Alternative name Human CD195 (CCR5)
Immunogen CHO cells transfected with human CCR5
Format Purified, Liquid
Isotype IgG2a  (Matching secondary antibodies)
Clone HEK-1-85a
Description MAb to CD195 Monoclonal Antibody to Human CD195 (CCR5)
Specificity Recognizes the human CD195 cell surface antigen, a 45kD glycoprotein also known as CCR5. CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin and also serves as a co-receptor for the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes.

Application Details
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Application Notes Suitable for use in flow cytometry (1:50-1:100). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Concentration Lot specific
Purification Protein G chromatography. Source: Culture
Buffer PBS. Preservative: 0.09% Sodium azide
Storage Short-term (up to 2 weeks) store at 2-8°C. Long term, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
Restrictions For Research Use only

Publications
Application Details Alternatives Secondary Antibodies back to top

Publications Mueller, Kelly, Strange: "Pathways for internalization and recycling of the chemokine receptor CCR5." in: Blood, Vol. 99, Issue 3, pp. 785-91, 2002 (PubMed).

Alternatives
Application Details Publications Secondary Antibodies back to top

Alternatives for antigen "Chemokine (C-C Motif) Receptor 5 (CCR5)", type "Antibodies"
Hosts Rabbit (45), Rat (26), Mouse (21), Hamster (13), Goat (1)
Reactivities Human (86), Mouse (Murine) (33), Rat (Rattus) (20), Cow (Bovine) (2), Dog (Canine) (1), Zebrafish (Brachydanio rerio) (1)
Applications Flow Cytometry (FACS) (75), Western Blotting (WB) (30), Immunofluorescence (IF) (26), ELISA (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Enzyme Immunoassay (EIA) (8), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), ELISA (Detection) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Functional Studies (Func) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates PE (12), Biotin (7), FITC (6), RPE (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes N-Term (2), non pSer337/349 (1), pSer337 (1), pSer349 (1)