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FASL antibody (Fas Ligand (TNF Superfamily, Member 6))

Details for Product anti-FASL Antibody No. ABIN235135, Supplier: Login to see
Antigen
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
Alternatives
anti-Human FASL antibody for Flow Cytometry
Reactivity
Human
273
140
67
3
3
1
1
1
1
1
Host
Hamster
147
125
60
30
12
6
Clonality (Clone)
Monoclonal ()
Conjugate
This FASL antibody is un-conjugated
32
25
18
5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA
194
160
86
61
57
52
27
26
17
12
12
11
11
6
3
3
2
2
1
1
1
1
1
1
1
Supplier
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Immunogen Recombinant human Fas ligand.
Clone 4A5
Isotype IgG
Specificity Apoptosis or programmed-cell death is a physiological process essential for the normal development and maintenance or homeostasis in many organisms. This
Cross-Reactivity (Details) Cross-reactivity with other species has not been tested yet.
Characteristics MAb to Fas L, Monoclonal antibody to Fas L
Purification Ascites
Alternative Name Fas L (FASL Antibody Abstract)
Pathways Apoptosis, EGFR Signaling Pathway
Application Notes Flow cytometry: Recommended: 10 µg/mL as a final concentration ELISA Neutralization of soluble Fas ligand cytotoxic-activity.. Not suitable for immunoblotting. Each laboratory should determine an optimum working titer for use in its particular application.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute with 100 µL of distilled water.
Buffer Lyophilized from PBS containing 1 % sucrose.
Preservative Without preservative
Handling Advice Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized product at 2-8 °C. After reconstitution, aliquot and store for up to 3 months at -28 °C.
Background publications Sato, Kimura, Nakamura et al.: "An aggressive nasal lymphoma accompanied by high levels of soluble Fas ligand." in: British journal of haematology, Vol. 94, Issue 2, pp. 379-82, 1996 (PubMed).

Tanaka, Suda, Haze et al.: "Fas ligand in human serum." in: Nature medicine, Vol. 2, Issue 3, pp. 317-22, 1996 (PubMed).

Takahashi, Tanaka, Inazawa et al.: "Human Fas ligand: gene structure, chromosomal location and species specificity." in: International immunology, Vol. 6, Issue 10, pp. 1567-74, 1995 (PubMed).

Tanaka, Suda, Takahashi et al.: "Expression of the functional soluble form of human fas ligand in activated lymphocytes." in: The EMBO journal, Vol. 14, Issue 6, pp. 1129-35, 1995 (PubMed).

Nagata, Golstein: "The Fas death factor." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1449-56, 1995 (PubMed).

Alderson, Tough, Davis-Smith et al.: "Fas ligand mediates activation-induced cell death in human T lymphocytes." in: The Journal of experimental medicine, Vol. 181, Issue 1, pp. 71-7, 1995 (PubMed).

Suda, Takahashi, Golstein et al.: "Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family." in: Cell, Vol. 75, Issue 6, pp. 1169-78, 1994 (PubMed).