You are viewing an incomplete version of our website. Please click to reload the website as full version.

FASL antibody (Fas Ligand (TNF Superfamily, Member 6))

Details for Product anti-FASL Antibody No. ABIN235135, Supplier: Log in to see
Antigen
  • ALPS1B
  • APT1LG1
  • Apt1Lg1
  • APTL
  • CD95-L
  • CD95L
  • CD178
  • FAS
  • Fas-L
  • FASL
  • fasl
  • Fasl
  • Faslg
  • FASLG
  • gld
  • TNFRSF6
  • Tnfsf6
  • TNFSF6
  • zgc:162027
Alternatives
anti-Human FASL antibody for Flow Cytometry
Reactivity
Human
272
138
64
3
1
1
1
1
1
1
Host
Hamster
142
127
60
30
12
6
Clonality (Clone)
Monoclonal ()
Conjugate
This FASL antibody is un-conjugated
32
26
18
5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA
198
158
87
63
56
49
29
29
17
11
11
11
11
5
3
3
2
2
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen Recombinant human Fas ligand.
Clone 4A5
Isotype IgG
Specificity Apoptosis or programmed-cell death is a physiological process essential for the normal development and maintenance or homeostasis in many organisms. This
Cross-Reactivity (Details) Cross-reactivity with other species has not been tested yet.
Characteristics MAb to Fas L, Monoclonal antibody to Fas L
Purification Ascites
Alternative Name Fas L (FASL Antibody Abstract)
Pathways Apoptosis, EGFR Signaling Pathway
Application Notes Flow cytometry: Recommended: 10 µg/mL as a final concentration ELISA Neutralization of soluble Fas ligand cytotoxic-activity.. Not suitable for immunoblotting. Each laboratory should determine an optimum working titer for use in its particular application.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute with 100 µL of distilled water.
Buffer Lyophilized from PBS containing 1 % sucrose.
Preservative Without preservative
Handling Advice Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized product at 2-8 °C. After reconstitution, aliquot and store for up to 3 months at -28 °C.
Background publications Sato, Kimura, Nakamura, Murakami, Yoshida, Tanaka, Nagata, Kanatani, Wakimoto, Nagata, Motoyoshi: "An aggressive nasal lymphoma accompanied by high levels of soluble Fas ligand." in: British journal of haematology, Vol. 94, Issue 2, pp. 379-82, 1996 (PubMed).

Tanaka, Suda, Haze, Nakamura, Sato, Kimura, Motoyoshi, Mizuki, Tagawa, Ohga, Hatake, Drummond, Nagata: "Fas ligand in human serum." in: Nature medicine, Vol. 2, Issue 3, pp. 317-22, 1996 (PubMed).

Nagata, Golstein: "The Fas death factor." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1449-56, 1995 (PubMed).

Takahashi, Tanaka, Inazawa, Abe, Suda, Nagata: "Human Fas ligand: gene structure, chromosomal location and species specificity." in: International immunology, Vol. 6, Issue 10, pp. 1567-74, 1995 (PubMed).

Tanaka, Suda, Takahashi, Nagata: "Expression of the functional soluble form of human fas ligand in activated lymphocytes." in: The EMBO journal, Vol. 14, Issue 6, pp. 1129-35, 1995 (PubMed).

Alderson, Tough, Davis-Smith, Braddy, Falk, Schooley, Goodwin, Smith, Ramsdell, Lynch: "Fas ligand mediates activation-induced cell death in human T lymphocytes." in: The Journal of experimental medicine, Vol. 181, Issue 1, pp. 71-7, 1995 (PubMed).

Suda, Takahashi, Golstein, Nagata: "Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family." in: Cell, Vol. 75, Issue 6, pp. 1169-78, 1994 (PubMed).