Prion Protein (PRNP) (AA 93-109) antibody

Details for Product No. ABIN236109
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Antigen
Synonyms
cjd, prp, prion, prp(c), MGC84114, PRP, BIMP2, CARMA2, PSORS2, PSS1, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30, PRPC, Prp, SIP, AA960666, AI325101, PrP, PrPC ... show more
cjd, prp, prion, prp(c), MGC84114, PRP, BIMP2, CARMA2, PSORS2, PSS1, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30, PRPC, Prp, SIP, AA960666, AI325101, PrP, PrPC, PrPSc, Prn-i, Prn-p, Sinc, prP27-30, prP33-35C, Prn, PRNP show less
Epitope
AA 93-109
(22), (11), (7), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Mammalian
(97), (61), (48), (44), (28), (6), (6), (6), (6), (3), (3), (2), (1), (1), (1), (1)
Host
Mouse
(71), (57), (19), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
(106), (74), (43), (35), (20), (15), (14), (13), (5), (4), (4), (3)
Pubmed 4 references available
Quantity 0.2 mg
Options
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Catalog No. ABIN236109
1,036.20 $
Plus shipping costs $45.00 and if applicable $26.40 dry ice

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Full-length recombinant PrP
Clone 6D11
Isotype IgG2a
Specificity Reacts with both the PrPc and PrPsc forms. Reacts with human, bovine, sheep, mule deer, elk, mouse and hamster PrP.
Characteristics MAb to Prion Protein, Monoclonal antibody to Prion Protein (AA 93-109)
Purification Purified
Alternative Name Prion Protein
Application Notes Western blot ELISA Immunohistochemistry: Epitope must be re-exposed in fixed tissues by pretreatment using one of the following procedures: 70 % Formic acid for 10-30 minutes at room temperature. Hydrolytic autoclaving Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS.
Preservative Without preservative
Handling Advice Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.
Do not store antibody diluted below 50 µg/mL in the absence of protein (i.e. add 2 % BSA).
Storage -20 °C
Storage Comment Upon receipt, store undiluted at -20 °C to -70 °C.
General Kascsak, Rubenstein, Merz et al.: "Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins." in: Journal of virology, Vol. 61, Issue 12, pp. 3688-93, 1987 (PubMed).

Kascsak, Tonna-DeMasi, Fersko et al.: "The role of antibodies to PrP in the diagnosis of transmissible spongiform encephalopathies." in: Developments in biological standardization, Vol. 80, pp. 141-51, 1994 (PubMed).

Sigurdsson, Sy, Li et al.: "Anti-prion antibodies for prophylaxis following prion exposure in mice." in: Neuroscience letters, Vol. 336, Issue 3, pp. 185-7, 2002 (PubMed).

Adler, Zeiler, Kryukov et al.: "Small, highly structured RNAs participate in the conversion of human recombinant PrP(Sen) to PrP(Res) in vitro." in: Journal of molecular biology, Vol. 332, Issue 1, pp. 47-57, 2003 (PubMed).

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