Amino-terminal Enhancer of Split (AES) (C-Term) antibody

Antigen: Amino-terminal Enhancer of Split (AES)

Synonyms: GRG, ESP1, GRG5, TLE5, AES-1, AES-2, Grg, Grg5, AL024115, MGC124620, AES, MGC64216, zgc:64216, aes, MGC68432, grg, esp1, grg5, tle5, aes-1, aes-2

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN236741

Additional Information

Immunogen: Synthetic peptide corresponding to 16 amino acids near the carboxy terminus of human AES (Genbank accession No. NP_945320)

Format: Liquid

Description: Rabbit anti AES, C-terminal Rabbit Antibody to Human Amino-Terminal Enhancer of Split (AES), C-terminal

Specificity: Reacts with human, mouse and rat AES.

Application Details

Application Notes: Suitable for use in Western blot (1 ? 2ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography.

Buffer: PBS. Preservative: 0.02% Sodium azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Miyasaka, Choudhury, Hou et al.: "Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein." in: European journal of biochemistry / FEBS, Vol. 216, Issue 1, pp. 343-52, 1993 (PubMed).

Chen, Courey: "Groucho/TLE family proteins and transcriptional repression." in: Gene, Vol. 249, Issue 1-2, pp. 1-16, 2000 (PubMed).

Jan, Matter, Pai et al.: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, 2004 (PubMed).

Martin, Vuori: "Regulation of Bcl-2 proteins during anoikis and amorphosis." in: Biochimica et biophysica acta, Vol. 1692, Issue 2-3, pp. 145-57, 2004 (PubMed).