Amyloid beta (A4) Precursor Protein (APP) (AA 653-662) antibody

Details for Product No. ABIN236746
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Antigen
Synonyms
APP, APP-like, APPL, Abeta, BcDNA:GH04413, CG7727, Dmel\\CG7727, EG:65F1.5, appl, aaa, abeta, abpp, ad1, appi, ctfgamma, cvap, pn2, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Abpp, Adap, ... show more
APP, APP-like, APPL, Abeta, BcDNA:GH04413, CG7727, Dmel\\CG7727, EG:65F1.5, appl, aaa, abeta, abpp, ad1, appi, ctfgamma, cvap, pn2, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp, app, wu:fj34d10, wu:fk65e12, zgc:85740 show less
Epitope
AA 653-662
(115), (87), (32), (30), (25), (13), (13), (10), (10), (10), (9), (8), (7), (7), (6), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(697), (355), (294), (212), (202), (196), (190), (71), (13), (13), (4), (2), (1), (1), (1), (1)
Host
Rabbit
(494), (197), (41), (6), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(29), (26), (24), (17), (17), (17), (17), (17), (17), (17), (17), (9), (5), (5), (4), (4), (4), (4), (2), (2)
Application
Western Blotting (WB)
(469), (245), (177), (159), (156), (61), (48), (42), (29), (23), (7), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 100 μg
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Catalog No. ABIN236746
481.80 $
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  • +1 404 474 4654
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Immunogen A peptide corresponding to AA 653 to 662 of human amyloid A4 protein precursor (APP) (1) or 1 to 10 of the 4K Amyloid beta peptide generated by beta- and gamma-secretase cleavages.(2) The peptide sequences are identical to those of rabbit, pig, bovine, guinea pig and chicken.
Specificity Amyloid precursor protein (AA 653-662) and Amyloid beta (AA 1-10).
Cross-Reactivity (Details) Human, mouse and rat reactive.
Characteristics Rabbit anti Amyloid Precursor Pro.(AA653-662), Rabbit antibody to Human Amyloid Precursor Protein (APP), AA 653-662
Purification Immuno Affinity Chromatography
Alternative Name Amyloid Precursor Protein (APP)
Research Area Neurology, Alzheimer's Disease
Application Notes Suitable for use in Western blot (0.5-1.0 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS, 0.02 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8 °C.
Expiry Date 12 months
General Ponte, Gonzalez-DeWhitt, Schilling et al.: "A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors." in: Nature, Vol. 331, Issue 6156, pp. 525-7, 1988 (PubMed).

Selkoe: "Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease." in: Annual review of cell biology, Vol. 10, pp. 373-403, 1995 (PubMed).

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