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Amyloid beta (A4) Precursor Protein (APP) (Precursor, AA 653-662) antibody

Antigen

Amyloid beta (A4) Precursor Protein (APP)
Synonyms APP, APP-like, APPL, Abeta, BcDNA:GH04413, EG:65F1.5, DmelCG7727, CG7727, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma
Binding Site
Alternatives

Precursor, AA 653-662
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
2 references available
Catalog no. ABIN236746
Quantity 100ug  (0.5mg/ml)
Price 468.60 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Amyloid Precursor Protein (APP)
Immunogen A peptide corresponding to amino acids 653 to 662 of human amyloid A4 protein precursor (APP) (1) or 1 to 10 of the 4K Amyloid beta peptide generated by beta- and gamma-secretase cleavages.(2) The peptide sequences are identical to those of rabbit, pig, bovine, guinea pig and chicken.
Format Liquid
Description Rabbit A’ Amyloid Precursor Pro.(a.a.653-662) Rabbit Antibody to Human Amyloid Precursor Protein (APP), amino acids 653-662
Specificity Amyloid precursor protein (a.a. 653-662) and Amyloid beta (a.a. 1-10). Human, mouse and rat reactive.

Application Details
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Application Notes Suitable for use in Western blot (0.5-1.0ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Concentration 0.5mg/ml
Purification Immunoaffinity chromatography
Buffer PBS. Preservative: 0.02% Sodium azide
Storage Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Ponte, Gonzalez-DeWhitt, Schilling et al.: "A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors." in: Nature, Vol. 331, Issue 6156, pp. 525-7, 1988 (PubMed).

Selkoe: "Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease." in: Annual review of cell biology, Vol. 10, pp. 373-403, 1995 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Amyloid beta (A4) Precursor Protein (APP)", type "Antibodies"
Hosts Rabbit (233), Mouse (67), Goat (34), Chicken (3)
Reactivities Human (298), Mouse (Murine) (146), Rat (Rattus) (134), Cow (Bovine) (75), Dog (Canine) (70), Chicken (69), Pig (Porcine) (68), Horse (Equine) (56), Monkey (9), Sheep (Ovine) (5), Rabbit (3), Guinea Pig (2), Xenopus laevis (2), Zebrafish (2), Cat (Feline) (1), Fruit Fly (Drosophila melanogaster) (1), Primate (1)
Applications Western Blotting (WB) (238), ELISA (123), Immunofluorescence (IF) (84), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (75), Immunohistochemistry (IHC) (62), Immunoprecipitation (IP) (23), Flow Cytometry (FACS) (12), Immunohistochemistry (Fixed) (IHC (fx)) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (8), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Immunocytochemistry (ICC) (5), Immunoelectron Microscopy (IEM) (2), Dot Blot (Dot) (1), Enzyme Immunoassay (EIA) (1)
Conjugates Alexa Fluor 350 (8), Alexa Fluor 488 (8), Alexa Fluor 555 (8), Alexa Fluor 647 (8), PE,Cy5.5 (8), Biotin (4), FITC (4), HRP (3), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2)
Epitopes N-Term (26), C-Term (21), Transcript Variant 1 (10), pThr668 (10), pThr743 (9), pSer198 (6), pSer730 (6), pTyr757 (5), AA 44-63 (4), AA 737-751 (4), AA 292-312 (3), Internal Region (3), Thr668 (3), AA 18-289 (2), AA 653-662 (2), AA 660-669 (2), AA 681-695 (2), AA 747-761 (2), Frameshift Mutant (2), pTyr756 (2), AA 1-14 (1), AA 1-16 (1), AA 339-348 (1), AA 350-450 (1), AA 36-42 (1), AA 671-685 (1), AA 73-7 (1), C-Term,Asp672 (1), Center (1), Extracellular Domain (1), Frameshift Mutant, AA 339-348 (1), Frameshift Mutant, C-Term (1), KPI Domain (1), N-Term,AA 18-32 (1), OX-2 Domain (1), Precursor, C-Term, AA 737-751 (1), Ser730 (1), Thr743, Thr668 (1), Tyr756 (1), Wild Type (1), pSer129 (1), pSer182 (1), pSer264 (1), pSer347 (1), pSer498,pSer490 (1), pThr743, pThr668 (1)