Anthrax Toxin Receptor-Like (ANTXRL) (C-Term) antibody

Details for Product No. ABIN236765
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Antigen
Epitope
C-Term
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
Pubmed 4 references available
Quantity 100 μg
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Catalog No. ABIN236765
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Immunogen Synthetic peptide corresponding to 13 AA near the C-terminal of human ATR (Genbank accession no. NP_115584).
Specificity Human Anthrax Toxin Receptor (ATR, TEM8). Recognizes only the 60 kDa isoform. Reacts with human, mouse and rat.
Cross-Reactivity (Details) Reacts with human, mouse and rat.
Characteristics Rabbit anti Anthrax Toxin Recep., Rabbit antibody to Human Anthrax Toxin Receptor (ATR), C-terminal
Purification Immuno Affinity Chromatography
Alternative Name Anthrax Toxin Receptor (ATR)
Application Notes Suitable for use in Western blot (1-2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.02 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8 °C.
General Molloy, Bresnahan, Leppla et al.: "Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen." in: The Journal of biological chemistry, Vol. 267, Issue 23, pp. 16396-402, 1992 (PubMed).

Duesbery, Webb, Leppla et al.: "Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor." in: Science (New York, N.Y.), Vol. 280, Issue 5364, pp. 734-7, 1998 (PubMed).

Carson-Walter, Watkins, Nanda et al.: "Cell surface tumor endothelial markers are conserved in mice and humans." in: Cancer research, Vol. 61, Issue 18, pp. 6649-55, 2001 (PubMed).

Bradley, Mogridge, Mourez et al.: "Identification of the cellular receptor for anthrax toxin." in: Nature, Vol. 414, Issue 6860, pp. 225-9, 2001 (PubMed).

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