Anthrax Toxin Receptor-Like (ANTXRL) (Middle Region) antibody

Details for Product No. ABIN236766
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Antigen
Synonyms 1700112N15Rik, 4933430J11
Epitope
Middle Region
(1)
Reactivity
Human
(1)
Host
Rabbit
(1)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(1)
Pubmed 4 references available
Quantity 100 µg
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Catalog No. ABIN236766
470.07 $
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Immunogen Synthetic peptide corresponding to 13 AA near the center of human ATR (Genbank accession no. NP_444262).
Specificity Human Anthrax Toxin receptor (ATR, TEM8). Recognizes all three isoforms (36, 40 and 60kDa).
Cross-Reactivity (Details) Reacts with human, mouse and rat.
Characteristics Rabbit anti Anthrax Toxin Recep., Rabbit antibody to Human Anthrax Toxin Receptor (ATR), Middle region
Purification Immuno Affinity Chromatography
Alternative Name Anthrax Toxin Receptor (ATR)
Application Notes Suitable for use in Immunohistochemistry (2 µg/mL) and Western blot (0.5-1.0 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to 1 year) at 2-8°C.
Expiry Date 12 months
General Molloy, Bresnahan, Leppla et al.: "Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen." in: The Journal of biological chemistry, Vol. 267, Issue 23, pp. 16396-402, 1992 (PubMed).

Duesbery, Webb, Leppla et al.: "Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor." in: Science (New York, N.Y.), Vol. 280, Issue 5364, pp. 734-7, 1998 (PubMed).

Carson-Walter, Watkins, Nanda et al.: "Cell surface tumor endothelial markers are conserved in mice and humans." in: Cancer research, Vol. 61, Issue 18, pp. 6649-55, 2001 (PubMed).

Bradley, Mogridge, Mourez et al.: "Identification of the cellular receptor for anthrax toxin." in: Nature, Vol. 414, Issue 6860, pp. 225-9, 2001 (PubMed).

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