Bacillus Anthracis Protective Antigen (PA) (Middle) antibody

Antigen: Bacillus Anthracis Protective Antigen (PA)

Epitope: Middle

Clonality: Polyclonal

Host: Rabbit

Application: ELISA

Catalog no.: ABIN236848

Additional Information

Alternative name: Bacillus anthracis (Anthrax) Protective Antigen (PA), Middle region

Immunogen: Synthetic peptide corresponding to 16 amino acids near the middle of the Anthrax protective antigen protein (Genbank accession no. AAF86457)

Format: Affinity-purified, Liquid

Description: Rabbit anti B. anthracis (PA) Rabbit Antibody to Bacillus anthracis (Anthrax) Protective Antigen (PA), Middle region

Specificity: Bacillus anthracis (Anthrax) Protective Antigen (PA), Middle region

Application Details

Application Notes: Suitable for use in ELISA (detects 10ng of free peptide at 1ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: 1mg/ml

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium azide

Storage: Store (up to 1 year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Publications: Singh, Klimpel, Goel et al.: "Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells." in: Infection and immunity, Vol. 67, Issue 4, pp. 1853-9, 1999 (PubMed).

Bradley, Mogridge, Mourez et al.: "Identification of the cellular receptor for anthrax toxin." in: Nature, Vol. 414, Issue 6860, pp. 225-9, 2001 (PubMed).

Swartz: "Recognition and management of anthrax--an update." in: The New England journal of medicine, Vol. 345, Issue 22, pp. 1621-6, 2001 (PubMed).

Scobie, Rainey, Bradley et al.: "Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 9, pp. 5170-4, 2003 (PubMed).

Moayeri, Leppla: "The roles of anthrax toxin in pathogenesis." in: Current opinion in microbiology, Vol. 7, Issue 1, pp. 19-24, 2004 (PubMed).