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Details for Product No. ABIN236934

Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (C-Term) antibody

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Synonyms cbl, Cbl-2, c-Cbl, 4732447J05Rik, C-CBL, CBL2, FRA11B, NSLL, RNF55, RGD1561386, c-cbl-like
»Alternatives C-Term
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN236934
Quantity 100 µg
474.47 $   Plus shipping costs $45.00
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Availability Will be delivered in 4 to 5 Business Days
Immunogen Synthetic peptide corresponding to 14 AA near the carboxy terminal of human cbl (Genbank accession No. P22681)
Specificity Reacts with the carboxy terminus of human, mouse and rat c-Cbl. The mammalian cbl family of ubiquitin ligases consists of three homologs known as c-Cbl, Cbl-B and Cbl-3. Of the three known homologs in the cbl family this antibody reacts specifically with c-Cbl. Multiple isoforms of c-Cbl have been reported.
Characteristics Rabbit anti Cbl, Rabbit antibody to Casitas B-lineage Lymphoma Proto-oncogene (Cbl)
Purification Ion Exchange Chromatography
Alternative Name Casitas B-lineage Lymphoma Proto-oncogene (Cbl)
Application Notes Suitable for use in Western blot (0.5-1 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8°C.
Expiry Date 12 months
Weissman: "Themes and variations on ubiquitylation." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 3, pp. 169-78, 2001 (PubMed).

Thien, Langdon: "c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses." in: The Biochemical journal, Vol. 391, Issue Pt 2, pp. 153-66, 2005 (PubMed).

Swaminathan, Tsygankov: "The Cbl family proteins: ring leaders in regulation of cell signaling." in: Journal of cellular physiology, Vol. 209, Issue 1, pp. 21-43, 2006 (PubMed).

Alternatives for antigen "Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL)", type "Antibodies"
Hosts (178), (21), (10)
Reactivities (202), (134), (132), (62), (50), (50), (24)
Applications (135), (82), (60), (50), (39), (37), (20), (17), (9), (3), (3), (3), (2), (1)
Conjugates (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6)
Epitopes (32), (28), (19), (18), (18), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)