Caspase 1 (CASP1) (Middle Region) antibody

Details for Product No. ABIN236935
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Antigen
Synonyms CG5370, DCP-1, DCP1, Dcp1, Dmel\\CG5370, ccp1, dcp-1, dcp1, l(2)01862, l(2)02132, Ice, ICE, Il1bc, IL1BC, P45, CASP1
Epitope
Middle Region
(33), (15), (8), (8), (6), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(149), (49), (43), (5), (4), (1), (1), (1), (1), (1)
Host
Rabbit
(158), (6), (4), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(141), (90), (63), (57), (18), (14), (14), (12), (10), (3), (1), (1)
Pubmed 7 references available
Quantity 100 μg
Options
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Catalog No. ABIN236935
514.80 $
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Immunogen 15 amino acid peptide from near the middle of human Caspase-1 (Genbank accession No. NP_150364).
Specificity Human Caspase-1. Depending on cell lines or tissues used, other cleavage products may be observed.
Characteristics Rabbit anti Caspase 1 (Middle), Rabbit antibody to Human Caspase-1 (Middle)
Purification Immuno Affinity Chromatography
Alternative Name Caspase-1
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (0.5 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8 °C.
General Kostura, Tocci, Limjuco et al.: "Identification of a monocyte specific pre-interleukin 1 beta convertase activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 14, pp. 5227-31, 1989 (PubMed).

Kuida, Lippke, Ku et al.: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995 (PubMed).

Yuan, Shaham, Ledoux et al.: "The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme." in: Cell, Vol. 75, Issue 4, pp. 641-52, 1993 (PubMed).

Miura, Zhu, Rotello et al.: "Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3." in: Cell, Vol. 75, Issue 4, pp. 653-60, 1993 (PubMed).

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

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