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Details for Product No. ABIN236936

Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) (C-Term) antibody

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Synonyms Ice, Il1bc, ICE, P45, IL1BC, CASP1, CG5370, DCP-1, DCP1, Dcp1, Dmel\\CG5370, ccp1, dcp-1, dcp1, l(2)01862, l(2)02132
»Alternatives C-Term
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 7 references available
Catalog no. ABIN236936
Quantity 100 µg
481.80 $   Plus shipping costs $45.00
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Availability Will be delivered in 4 to 5 Business Days
Immunogen 16 amino acid peptide from near the carboxy-terminus of human Caspase-1 (Genbank accession No. NP_150364).
Specificity Human Caspase-1, C-terminal. Depending on cell lines or tissues used, non-cleaved or cleavage products may be observed.
Characteristics Rabbit anti Caspase 1 (CT), Rabbit antibody to Human Caspase-1, C-terminal
Purification Immuno Affinity Purified
Alternative Name Caspase-1
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (0.5 µg/mL) and immunohistochemistry (2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store at 2-8°C.
Kostura, Tocci, Limjuco et al.: "Identification of a monocyte specific pre-interleukin 1 beta convertase activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 14, pp. 5227-31, 1989 (PubMed).

Kuida, Lippke, Ku et al.: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995 (PubMed).

Yuan, Shaham, Ledoux et al.: "The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme." in: Cell, Vol. 75, Issue 4, pp. 641-52, 1993 (PubMed).

Miura, Zhu, Rotello et al.: "Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3." in: Cell, Vol. 75, Issue 4, pp. 653-60, 1993 (PubMed).

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

Alternatives for antigen "Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1)", type "Antibodies"
Hosts (104), (8), (4), (1)
Reactivities (110), (37), (30), (1), (1), (1), (1), (1)
Applications (95), (51), (38), (32), (16), (10), (9), (4), (3), (3), (3), (2), (1), (1), (1)
Conjugates (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (30), (8), (8), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)