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Details for Product No. ABIN236944

Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Middle Region) antibody

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Antigen
Synonyms TX, ICH-2, Mih1/TX, ICEREL-II, ICE(rel)II, Casp11, Caspl, ich-3, CASP4
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN236944
Quantity 100 µg
Price
481.80 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 4 to 5 Business Days
Immunogen 15 amino acid peptide from near the center of human Caspase-4 (Genbank accession No. AAA86890).
Specificity Human Caspase-4. Depending on cell lines or tissues used, other cleavage products may be observed.
Characteristics Rabbit anti Caspase 4 (Middle), Rabbit antibody to Human Caspase-4, (Middle)
Purification Immuno Affinity Chromatography
Alternative Name Caspase-4
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store at 2-8°C.
Kuida, Lippke, Ku et al.: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995 (PubMed).

Kamens, Paskind, Hugunin et al.: "Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 15250-6, 1995 (PubMed).

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003 (PubMed).

Hitomi, Katayama, Eguchi et al.: "Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death." in: The Journal of cell biology, Vol. 165, Issue 3, pp. 347-56, 2004 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Alternatives for antigen "Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4)", type "Antibodies"
Hosts (112), (11), (9), (6), (6)
Reactivities (103), (61), (34), (12), (5), (2)
Applications (122), (47), (40), (30), (19), (11), (6), (5), (4), (3), (3), (1), (1)
Conjugates (8), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (25), (12), (7), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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