Aspase-5 (Middle Region) antibody

Details for Product No. ABIN236946
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Antigen
Epitope
Middle Region
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
Pubmed 5 references available
Quantity 100 µg
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Catalog No. ABIN236946
481.80 $
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Immunogen 14 amino acid peptide from near the center of human Caspase-5 (Genbank accession No. P51878).
Specificity Human Caspase-5. Depending on cell lines or tissues used, other cleavage products may be observed.
Characteristics Rabbit anti Caspase 5 (Middle), Rabbit antibody to Human Caspase-5, (Middle)
Purification Immuno Affinity Chromatography
Application Notes Suitable for use in Western blot (0.5-1.0 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store at 2-8°C.
General Kuida, Lippke, Ku et al.: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995 (PubMed).

Lin, Choi, Porter: "Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma." in: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39920-6, 2001 (PubMed).

Martinon, Burns, Tschopp: "The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta." in: Molecular cell, Vol. 10, Issue 2, pp. 417-26, 2002 (PubMed).

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

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