aspase-5 (Middle Region) antibody

Antigen: aspase-5

Binding Site: Middle Region

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN236946

Additional Information

Immunogen: 14 amino acid peptide from near the center of human Caspase-5 (Genbank accession No. P51878).

Format: Liquid

Description: Rabbit anti Caspase 5 (Middle) Rabbit Antibody to Human Caspase-5, (Middle)

Specificity: Human Caspase-5. Depending on cell lines or tissues used, other cleavage products may be observed.

Application Details

Application Notes: Suitable for use in Western blot (0.5-1.0ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Kuida, Lippke, Ku et al.: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995 (PubMed).

Lin, Choi, Porter: "Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma." in: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39920-6, 2001 (PubMed).

Martinon, Burns, Tschopp: "The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta." in: Molecular cell, Vol. 10, Issue 2, pp. 417-26, 2002 (PubMed).

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).