Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (N-Term) antibody

Details for Product No. ABIN236948
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Antigen
Synonyms MCH2, Mch2, mCASP-6, xCaspase-6, mch2, caspase-6, zgc:112960, CASP6, casp6
Epitope
N-Term
(40), (27), (22), (10), (7), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(173), (91), (76), (13), (7), (2), (1)
Host
Rabbit
(157), (32), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application
Western Blotting (WB)
(148), (82), (55), (45), (40), (31), (22), (15), (8), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
Catalog no. ABIN236948
Quantity 100 µg
Price
481.80 $   Plus shipping costs $45.00
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Immunogen 15 amino acid peptide from near the amino-terminus of human Caspase-6 (Genbank accession No. NP_001217).
Specificity Human Caspase-6, N-terminal. Depending on cell lines or tissues used, either full length or other cleavage products may be observed.
Characteristics Rabbit anti Caspase 6 (NT), Rabbit antibody to Human Caspase-6, N-terminal
Purification Immuno Affinity Chromatography
Alternative Name Caspase-6
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (0.5 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store at 2-8°C.
General Fernandes-Alnemri, Litwack, Alnemri: "Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family." in: Cancer research, Vol. 55, Issue 13, pp. 2737-42, 1995 (PubMed).

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999 (PubMed).

LeBlanc, Liu, Goodyer et al.: "Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease." in: The Journal of biological chemistry, Vol. 274, Issue 33, pp. 23426-36, 1999 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

Hosts (157), (32), (2)
Reactivities (173), (91), (76), (13), (7), (2), (1)
Applications (148), (82), (55), (45), (40), (31), (22), (15), (8), (2), (2), (1), (1), (1), (1)
Conjugates (8), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (40), (27), (22), (10), (7), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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