Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (C-Term) antibody

Details for Product No. ABIN236950
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Antigen
Synonyms xCaspase-7, caspase-7, caspase7, cmh-1, ice-lap3, mch3, CASP7, AI314680, CMH-1, ICE-IAP3, Mch3, mCASP-7, CASP-7, ICE-LAP3, LICE2, MCH3, Caspase-7, MCH3/SCA-2, SCA-2
Epitope
C-Term
(21), (15), (10), (8), (6), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(172), (85), (64), (26), (24), (13), (12), (3), (3), (2), (1), (1), (1)
Host
Rabbit
(142), (36), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(153), (70), (51), (44), (20), (20), (10), (9), (6), (3), (2)
Pubmed 5 references available
Quantity 100 μg
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Request Want additional data for this product?

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Catalog No. ABIN236950
481.80 $
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Immunogen 16 amino acid peptide from near the carboxy-terminus of human Caspase-7 (Genbank accession No. P55210).
Specificity Reacts with human, mouse and rat Caspase-7, C-terminal. Depending on cell lines or tissues used, either full length or other cleavage products may be observed.
Characteristics Rabbit anti Caspase 7 (CT), Rabbit antibody to Human Caspase-7, C-terminal
Purification Immuno Affinity Chromatography
Alternative Name Caspase-7
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (0.5 µg/mL) and immunohistochemistry (2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8 °C.
General Juan, McNiece, Argento et al.: "Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3." in: Genomics, Vol. 40, Issue 1, pp. 86-93, 1997 (PubMed).

Deveraux, Takahashi, Salvesen et al.: "X-linked IAP is a direct inhibitor of cell-death proteases." in: Nature, Vol. 388, Issue 6639, pp. 300-4, 1997 (PubMed).

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

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