Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (Middle Region) antibody

Details for Product No. ABIN236952
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Antigen
Synonyms ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5, CASP-8, Mch5, caspase-8, zgc:92075, casp8-A, xCaspase-8, casp8, CASP8
Epitope
Middle Region
(29), (13), (7), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(207), (70), (58), (28), (13), (12), (12), (9), (5), (2), (1), (1)
Host
Rabbit
(178), (55), (6), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(205), (86), (51), (49), (32), (31), (18), (15), (11), (10), (4), (2), (2), (2), (2), (1), (1)
Pubmed 6 references available
Catalog no. ABIN236952
Quantity 100 µg
Price
423.13 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 4 to 5 Business Days

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen 15 amino acid peptide from near the center of human Caspase-8 isoform E (Genbank accession No. NP_203522).
Specificity Reacts with human and mouse Caspase-8. Depending on cell lines or tissues used, either full length or other cleavage products may be observed.
Characteristics Rabbit anti Caspase 8 (Middle), Rabbit antibody to Human Caspase-8 (Middle)
Purification Immuno Affinity Chromatography
Alternative Name Caspase-8
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (0.5 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store at 2-8°C.
General Muzio, Chinnaiyan, Kischkel et al.: "FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex." in: Cell, Vol. 85, Issue 6, pp. 817-27, 1996 (PubMed).

Irmler, Thome, Hahne et al.: "Inhibition of death receptor signals by cellular FLIP." in: Nature, Vol. 388, Issue 6638, pp. 190-5, 1997 (PubMed).

Ashkenazi, Dixit: "Death receptors: signaling and modulation." in: Science (New York, N.Y.), Vol. 281, Issue 5381, pp. 1305-8, 1998 (PubMed).

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

Hosts (178), (55), (6), (1)
Reactivities (207), (70), (58), (28), (13), (12), (12), (9), (5), (2), (1), (1)
Applications (205), (86), (51), (49), (32), (31), (18), (15), (11), (10), (4), (2), (2), (2), (2), (1), (1)
Conjugates (9), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (29), (13), (7), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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