anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (C-Term)

Details for Product anti-CASP8 Antibody No. ABIN236953
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Antigen
Epitope
C-Term
(41), (28), (14), (12), (10), (9), (9), (8), (7), (6), (5), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(284), (77), (54), (20), (8), (4), (2), (1), (1), (1), (1)
Host
Rabbit
(253), (64), (8), (2), (1)
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
(14), (8), (7), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(294), (114), (73), (52), (43), (22), (18), (17), (16), (13), (10), (6), (6), (3), (2), (2), (2), (1), (1)
Pubmed 6 references available
Quantity 100 μg
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The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen 16 amino acid peptide from near the carboxy-terminus of human Caspase-8 isoform A (Genbank accession No. NP_001219).
Specificity Reacts with human, mouse and rat Caspase-8, C-terminal. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.
Characteristics Rabbit anti Caspase 8 (CT), Rabbit antibody to Human Caspase-8, C-terminal
Purification Immuno Affinity Chromatography
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Research Area Apoptosis/Necrosis
Application Notes Suitable for use in Western blot (0.5 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8 °C.
General Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005 (PubMed).

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004 (PubMed).

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999 (PubMed).

Ashkenazi, Dixit: "Death receptors: signaling and modulation." in: Science (New York, N.Y.), Vol. 281, Issue 5381, pp. 1305-8, 1998 (PubMed).

Irmler, Thome, Hahne et al.: "Inhibition of death receptor signals by cellular FLIP." in: Nature, Vol. 388, Issue 6638, pp. 190-5, 1997 (PubMed).

Muzio, Chinnaiyan, Kischkel et al.: "FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex." in: Cell, Vol. 85, Issue 6, pp. 817-27, 1996 (PubMed).

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Catalog No. ABIN236953
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