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Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 299-318), (Middle Region 2) antibody

Details for Product No. ABIN236956
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Antigen
Synonyms APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, AI115399, AW493809, CASP-9, Caspase-9, Mch6, Apaf3, Casp9_v1, Ice-Lap6, Casp-9-CTD, CASP9
Epitope
AA 299-318, Middle Region 2
(26), (22), (18), (18), (13), (8), (7), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(306), (108), (94), (17), (15), (12), (7), (6), (3), (3), (1)
Host
Rabbit
(316), (30), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1)
Application
Western Blotting (WB)
(294), (139), (69), (69), (51), (50), (39), (36), (14), (3), (2), (1)
Pubmed 4 references available
Quantity 100 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 4 to 5 Business Days
Catalog No. ABIN236956
481.80 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide corresponding to AA 299-318 of human caspase-9
Specificity Reacts with human caspase-9 and has no cross-reactivity with other members of the caspase family. Also known as Mch6/Apaf (IN2). Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNF-alpha, TRAIL, anti-CD-95, FADD and TRADD. (4) Caspase-9 is expressed in a variety of human tissues. (1, 2)
Characteristics Rabbit anti Caspase-9 (I20) (Intermed. Domain 2), Rabbit antibody to Caspase-9 (I20), Intermediate Domain 2
Purification Immuno Affinity Chromatography
Alternative Name Caspase-9
Research Area Apoptosis/Necrosis, Cancer
Application Notes Suitable for use in immunohistochemistry (2 µg/mL) and Western blot (1:1.000-1:2.000). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS, 0.02% Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8°C.
Expiry Date 12 months
General Duan, Orth, Chinnaiyan et al.: "ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B." in: The Journal of biological chemistry, Vol. 271, Issue 28, pp. 16720-4, 1996 (PubMed).

Srinivasula, Fernandes-Alnemri, Zangrilli et al.: "The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32." in: The Journal of biological chemistry, Vol. 271, Issue 43, pp. 27099-106, 1996 (PubMed).

Li, Nijhawan, Budihardjo et al.: "Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade." in: Cell, Vol. 91, Issue 4, pp. 479-89, 1997 (PubMed).

Pan, ORourke, Dixit: "Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex." in: The Journal of biological chemistry, Vol. 273, Issue 10, pp. 5841-5, 1998 (PubMed).

Hosts (316), (30), (1)
Reactivities (306), (108), (94), (17), (15), (12), (7), (6), (3), (3), (1)
Applications (294), (139), (69), (69), (51), (50), (39), (36), (14), (3), (2), (1)
Conjugates (9), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1)
Epitopes (26), (22), (18), (18), (13), (8), (7), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN236956
481.80 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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