Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibody

Antigen: Chemokine (C-C Motif) Receptor 3 (CCR3)

Synonyms: CKR3, CD193, CMKBR3, CC-CKR-3, MGC102841

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN236963

Additional Information

Alternative name: CC Chemokine Receptor 3 (CCR3)

Immunogen: Synthetic peptide corresponding to 14 amino acids near the carboxy terminus of human CCR3 (Genbank accession No. NP_847899).

Format: Liquid

Description: Rabbit anti CCR3, C-term. Rabbit Antibody to Human CC Chemokine Receptor 3 (CCR3), C-terminal

Specificity: Reacts with human, mouse and rat CCR3.

Application Details

Application Notes: Suitable for use in Western blot (1 ? 2ug/ml) and Immunohistochemistry (10ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Combadiere, Ahuja, Murphy: "Cloning and functional expression of a human eosinophil CC chemokine receptor." in: The Journal of biological chemistry, Vol. 270, Issue 28, pp. 16491-4, 1995 (PubMed).

Feng, Broder, Kennedy et al.: "HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 272, Issue 5263, pp. 872-7, 1996 (PubMed).

Deng, Liu, Ellmeier et al.: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996 (PubMed).

Choe, Farzan, Sun et al.: "The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates." in: Cell, Vol. 85, Issue 7, pp. 1135-48, 1996 (PubMed).

He, Chen, Farzan et al.: "CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia." in: Nature, Vol. 385, Issue 6617, pp. 645-9, 1997 (PubMed).

Zhang, He, Talal et al.: "In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5." in: Journal of virology, Vol. 72, Issue 6, pp. 5035-45, 1998 (PubMed).