anti-CCR3 antibody (Chemokine (C-C Motif) Receptor 3) (C-Term)

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Antigen
Synonyms CC-CKR-3, CD193, CKR3, CMKBR3, CC-CKR3, Cmkbr1l2, Cmkbr3
Epitope
C-Term
(28), (25), (14), (13), (6), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(162), (48), (33), (1)
Host
Rabbit
(115), (37), (16), (12)
Clonality
Polyclonal
Conjugate
This CCR3 antibody is un-conjugated
(16), (9), (8), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(98), (55), (53), (44), (38), (12), (11), (8), (5), (4), (3), (2), (2), (2), (2), (1), (1)
Pubmed 6 references available
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Quantity 100 μg
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Immunogen Synthetic peptide corresponding to 14 AA near the carboxy terminus of human CCR3 (Genbank accession No. NP_847899).
Specificity Reacts with human, mouse and rat CCR3.
Characteristics Rabbit anti CCR3, C-term., Rabbit antibody to Human CC Chemokine Receptor 3 (CCR3), C-terminal
Purification Immuno Affinity Chromatography
Alternative Name CC Chemokine Receptor 3 (CCR3) (CCR3 Antibody Abstract)
Application Notes Suitable for use in Western blot (1 - 2 µg/mL) and Immunohistochemistry (10 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8 °C.
Expiry Date 12 months
Background publications Zhang, He, Talal et al.: "In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5." in: Journal of virology, Vol. 72, Issue 6, pp. 5035-45, 1998 (PubMed).

He, Chen, Farzan et al.: "CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia." in: Nature, Vol. 385, Issue 6617, pp. 645-9, 1997 (PubMed).

Choe, Farzan, Sun et al.: "The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates." in: Cell, Vol. 85, Issue 7, pp. 1135-48, 1996 (PubMed).

Deng, Liu, Ellmeier et al.: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996 (PubMed).

Feng, Broder, Kennedy et al.: "HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 272, Issue 5263, pp. 872-7, 1996 (PubMed).

Combadiere, Ahuja, Murphy: "Cloning and functional expression of a human eosinophil CC chemokine receptor." in: The Journal of biological chemistry, Vol. 270, Issue 28, pp. 16491-4, 1995 (PubMed).

Catalog No. ABIN236963
$495.73
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