Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN237103

Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (Extracellular Loop), (AA 182-196) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E, Sdf1r, Cmkar4, PB-CKR, PBSF/SDF-1, CXCR4, cb403, zgc:109863, CXC-R4, CXCR-4, cd184, d2s201e, fb22, hm89, hsy3rr ... show more
Epitope
»Alternatives Extracellular Loop, AA 182-196
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 7 references available
Catalog no. ABIN237103
Quantity 100 µg
Price
468.60 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 4 to 5 Business Days
Immunogen Peptide corresponding to AA 182-196 in the second extracellular loop (EL) of human CXCR4.
Specificity Reacts with CXCR4 in human and mouse samples. Also known as fusion, LESTR and HUMSTR. CXCR4 is a principle co-receptor for T-cell trophic strains of HIV-1 fusion and entry of human white blood cells.
Characteristics Rabbit anti CXCR4 Extracellular Loop, Rabbit antibody to CXCR4, Extracellular Loop
Purification Immuno Affinity Chromatography
Alternative Name CXCR4
Research Area Cancer, Adaptive Immunity, Hematopoietic Progenitors, Innate Immunity, Chemokines, Receptors
Application Notes Suitable for use in Western blot (1:500-1:1.000), immunoprecipitation and immunocytochemistry. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.02% Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to 1 year) at 2-8°C.
Expiry Date 12 months
Feng, Broder, Kennedy et al.: "HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 272, Issue 5263, pp. 872-7, 1996 (PubMed).

Doranz, Rucker, Yi et al.: "A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors." in: Cell, Vol. 85, Issue 7, pp. 1149-58, 1996 (PubMed).

Berson, Long, Doranz et al.: "A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains." in: Journal of virology, Vol. 70, Issue 9, pp. 6288-95, 1996 (PubMed).

Lapham, Ouyang, Chandrasekhar et al.: "Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines." in: Science (New York, N.Y.), Vol. 274, Issue 5287, pp. 602-5, 1996 (PubMed).

Endres, Clapham, Marsh et al.: "CD4-independent infection by HIV-2 is mediated by fusin/CXCR4." in: Cell, Vol. 87, Issue 4, pp. 745-56, 1997 (PubMed).

Brelot, Heveker, Pleskoff et al.: "Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity." in: Journal of virology, Vol. 71, Issue 6, pp. 4744-51, 1997 (PubMed).

Lu, Berson, Chen et al.: "Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 12, pp. 6426-31, 1997 (PubMed).

Alternatives for antigen "Chemokine (C-X-C Motif) Receptor 4 (CXCR4)", type "Antibodies"
Hosts (171), (42), (25), (12), (1)
Reactivities (214), (112), (64), (30), (16), (12), (6), (3), (3), (2), (2)
Applications (156), (79), (74), (71), (40), (27), (26), (24), (20), (9), (8), (6), (4), (3), (1), (1), (1)
Conjugates (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (51), (17), (10), (10), (8), (6), (6), (6), (6), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Beacon