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Death Effector Domain Containing 2 (DEDD2) antibody

Antigen

Death Effector Domain Containing 2 (DEDD2)

Synonyms FLAME-3, DEDD2, MGC140424, MGC145883, DEFT, KE05, DEDD1, FLDED1, CASP8IP1, 2410050E11Rik, DEDD, MGC127710, DKFZp459K109
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
3 references available
Catalog no. ABIN237151
Quantity 100ug  (Lot specific)  (Variants)
Price 455.40 $   Plus shipping costs $45.00
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Additional Information

Alternative name DNA-binding Death effector Domain-containing protein 2 (DEDD2)
Immunogen Synthetic peptide corresponding to 11 amino acids near the amino terminus of Human DEDD2 (Genbank accession No. NP_579874).
Format Liquid
Description Rabbit anti DEDD 2 Rabbit Antibody to Human DNA-binding Death effector Domain-containing protein 2 (DEDD2)
Specificity Reacts with human, mouse and rat DEDD 2.

Application Details

Application Notes Suitable for use in Western blot (0.5 ? 1ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Concentration Lot specific
Purification DEAE column chromatography
Buffer PBS. Preservative: 0.02% Sodium Azide
Storage Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Restrictions For Research Use only

Publications

Roth, Stenner-Liewen, Pawlowski et al.: "Identification and characterization of DEDD2, a death effector domain-containing protein." in: The Journal of biological chemistry, Vol. 277, Issue 9, pp. 7501-8, 2002 (PubMed).

Alcivar, Hu, Tang et al.: "DEDD and DEDD2 associate with caspase-8/10 and signal cell death." in: Oncogene, Vol. 22, Issue 2, pp. 291-7, 2003 (PubMed).

Tibbetts, Zheng, Lenardo: "The death effector domain protein family: regulators of cellular homeostasis." in: Nature immunology, Vol. 4, Issue 5, pp. 404-9, 2003 (PubMed).

Alternatives

Alternatives for antigen "Death Effector Domain Containing 2 (DEDD2)", type "Antibodies"
Hosts Rabbit (47)
Reactivities Human (44), Mouse (Murine) (28), Rat (Rattus) (27), Cow (Bovine) (2), Dog (Canine) (2), Cat (Feline) (1), Chicken (1)
Applications Western Blotting (WB) (31), Immunofluorescence (IF) (15), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunoprecipitation (IP) (5), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (7), AA 144-129 (2), AA 175-193 (1), AA 210-228 (1), Center (1), Internal Region (1)