anti-LAMP2 antibody (Lysosomal-Associated Membrane Protein 2)

Details for Product anti-LAMP2 Antibody No. ABIN237777
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Antigen
Reactivity
Human
(226), (202), (32), (25), (18), (6), (1), (1)
Host
Rabbit
(152), (141), (109), (1)
Clonality
Polyclonal
Conjugate
This LAMP2 antibody is un-conjugated
(59), (39), (36), (21), (11), (11), (8), (8), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(191), (179), (94), (85), (75), (73), (54), (40), (35), (12), (10), (8), (4), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
Quantity 100 μg
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Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Synthetic peptide corresponding to 17 AA near the center of human LAMP-2 (Genbank accession No. NP_034815)
Specificity Reacts with human and mouse LAMP-2. Despite its predicted size, LAMP-2 migrates at 115 kDa in SDS-PAGE.
Characteristics Rabbit anti LAMP-2, Rabbit antibody to Human Lysosome Associated Membrane Protein 2 (LAMP-2)
Purification Immuno Affinity Chromatography
Alternative Name Lysosome Associated Membrane Protein 2 (LAMP-2) (LAMP2 Antibody Abstract)
Application Notes Suitable for use in Western blot (1 - 2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8 °C.
Expiry Date 12 months
General Gozuacik, Kimchi: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, 2004 (PubMed).

Kamada, Funakoshi, Shintani et al.: "Tor-mediated induction of autophagy via an Apg1 protein kinase complex." in: The Journal of cell biology, Vol. 150, Issue 6, pp. 1507-13, 2000 (PubMed).

Tanaka, Guhde, Suter et al.: "Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice." in: Nature, Vol. 406, Issue 6798, pp. 902-6, 2000 (PubMed).

Kisen, Tessitore, Costelli et al.: "Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells." in: Carcinogenesis, Vol. 14, Issue 12, pp. 2501-5, 1994 (PubMed).

Gough, Hatem, Fambrough: "The family of LAMP-2 proteins arises by alternative splicing from a single gene: characterization of the avian LAMP-2 gene and identification of mammalian homologs of LAMP-2b and LAMP-2c." in: DNA and cell biology, Vol. 14, Issue 10, pp. 863-7, 1995 (PubMed).

Granger, Green, Gabel et al.: "Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells." in: The Journal of biological chemistry, Vol. 265, Issue 20, pp. 12036-43, 1990 (PubMed).

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Catalog No. ABIN237777
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