NACHT Domain, Leucine-Rich-Repeat, and PYD-Containing Protein 1 (NALP1) (C-Term) antibody

Details for Product No. ABIN237836
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Antigen
Epitope
C-Term
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
Pubmed 4 references available
Quantity 100 μg
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Catalog No. ABIN237836
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Immunogen Synthetic peptide corresponding to 13 AA near the carboxy-terminal of human NALP1 (GenBank accession no. AAG30288).
Specificity Reacts with the C-terminus of Human NALP1.
Characteristics Rabbit anti NALP1, Rabbit antibody to Human NACHT domain, Leucine-rich-repeat, and PYD-containing Protein 1 (NALP1)
Purification Immuno Affinity Chromatography
Application Notes Suitable for use in Western blot (1 - 2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8 °C.
Expiry Date 12 months
General Hlaing, Guo, Dilley et al.: "Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins." in: The Journal of biological chemistry, Vol. 276, Issue 12, pp. 9230-8, 2001 (PubMed).

Chu, Pio, Xie et al.: "A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 12, pp. 9239-45, 2001 (PubMed).

Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

Sanz, Calasanz, Andreu et al.: "NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells." in: The Biochemical journal, Vol. 384, Issue Pt 2, pp. 281-6, 2004 (PubMed).

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