NACHT domain, Leucine-rich-repeat, and PYD-containing Protein 1 (NALP1) antibody

Antigen: NACHT domain, Leucine-rich-repeat, and PYD-containing Protein 1 (NALP1)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN237836

Additional Information

Immunogen: Synthetic peptide corresponding to 13 amino acids near the carboxy-terminal of human NALP1 (GenBank accession no. AAG30288).

Format: Liquid

Description: Rabbit anti NALP1 Rabbit Antibody to Human NACHT domain, Leucine-rich-repeat, and PYD-containing Protein 1 (NALP1)

Specificity: Reacts with the C-terminus of Human NALP1.

Application Details

Application Notes: Suitable for use in Western blot (1 ? 2ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Hlaing, Guo, Dilley et al.: "Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins." in: The Journal of biological chemistry, Vol. 276, Issue 12, pp. 9230-8, 2001 (PubMed).

Chu, Pio, Xie et al.: "A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 12, pp. 9239-45, 2001 (PubMed).

Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

Sanz, Calasanz, Andreu et al.: "NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells." in: The Biochemical journal, Vol. 384, Issue Pt 2, pp. 281-6, 2004 (PubMed).